n.serrano

TL2 Moderator · Galway

Contributes reviews on supplier material. Based in Galway.

Joined 20 April 2025 · last posted 5d

94Posts here

2Topics

0Solutions

187Likes received

141Likes given

21Badges

106Days visited

728Posts read

Recent activity

Full stream

Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #90 · Practice › Dosing & titration · 23 Jul 2026 · 22 likes Holding a dose indefinitely: the trials did not study indefinite holding at a non-maximum dose. The trials escalated to a target and then held that. What happens if you…
Spreadsheets: an appreciation — what changed since Replied, post #109 · Lounge › Off topic · 22 Jul 2026 · 1 like Picking up post #106: that is the part I would want checked first. Politics and public policy: healthcare policy that affects access to these compounds is relevant…
Journal club: what we got wrong in an earlier session Replied, post #96 · Evidence › Journal club · 18 Jul 2026 · 8 likes Critical appraisal template: (1) What did the trial set out to estimate? (2) Could the design answer that question? (3) Was the population sufficiently similar to your…
Request: tag synonyms surfaced in search Replied, post #19 · Meta › Feature requests · 16 Jul 2026 · 0 likes Use case: explain why you think the feature would help. "I would use this to..." makes the request concrete.
Pooling trials with different estimands Replied, post #98 · Evidence › Meta-analyses · 15 Jul 2026 · 3 likes Why forest plots are more informative than pooled numbers: they show the variation across studies, which tells you whether the effect is consistent or heterogeneous. A…
Coming back to: Solubility limits and what a cloudy solution is telling you Replied, post #40 · Pharmacology › Formulation chemistry · 14 Jul 2026 · 0 likes Preservatives: solutions for multi-dose vials contain preservatives (benzyl alcohol, phenol, or others) to inhibit microbial growth after the vial has been entered.…
Why the absence of controlled human data on BPC-157 matters more than people admit Replied, post #57 · Compounds › Repair & healing peptides · 10 Jul 2026 · 11 likes On post #53 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly…
Tracking a shortage from primary sources rather than rumour Replied, post #93 · Access › Shortages · 9 Jul 2026 · 22 likes post #92 is right about the mechanism and I think understates the practical bit. International supply chains: a shortage in one country does not mean shortage in…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #87 · Analytics › HPLC & UHPLC · 29 Jun 2026 · 3 likes On integration: where the baseline is drawn matters more than most people realise. On a clean chromatogram with well-resolved peaks the choice is inconsequential. On a…
When a dose reduction is the correct response to a side effect Replied, post #34 · Practice › Dosing & titration · 29 Jun 2026 · 0 likes Titrating on tolerability rather than on the calendar: some people escalate when they tolerate a dose well, others escalate on the prescribed schedule regardless. The…
Personal or family history of medullary thyroid carcinoma Replied, post #24 · Safety › Contraindications · 28 Jun 2026 · 0 likes Picking up post #21: that is the part I would want checked first. Pregnancy: these compounds are not approved for pregnancy. The potential risks outweigh potential…
Second pass at: When your prescriber and the evidence disagree Replied, post #39 · Clinical › Prescriber conversations · 22 Jun 2026 · 18 likes post #38 answers the question as asked. The question underneath it is different. Discussing off-label dosing: if you want to dose differently than the label specifies…