f.yildiz

TL2 Moderator · Bergen

Contributes reviews on supplier material. Based in Bergen.

Joined 2 February 2025 · last posted 9d

99 posts, newest first. Showing up to 150.

What is genuinely unknown about long-term amylin agonism Replied, post #57 · Compounds › Cagrilintide & amylin analogues · 19 Jul 2026 · 31 likes Cagrilintide molecular characteristics: it is a synthetic amylin analogue, substituted to prevent the amyloidogenicity of human amylin. The sequence is short and…
Why the absence of controlled human data on BPC-157 matters more than people admit Replied, post #62 · Compounds › Repair & healing peptides · 19 Jul 2026 · 1 like I read post #60 twice before replying, because I had assumed the opposite. Reading a preclinical wound-healing model: the model shows whether a mechanism is plausible…
Follow-up: How compounding permissions changed when supply normalised Replied, post #27 · Sourcing › Regulatory · 16 Jul 2026 · 0 likes Regulatory positions change: a compound's status today might differ from its status a year from now. Citing a regulatory position is worth doing only with a date…
Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #34 · Compounds › Retatrutide · 14 Jul 2026 · 3 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
How shortages have affected compounding permissions Replied, post #34 · Access › Shortages · 13 Jul 2026 · 2 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Journal club: what we got wrong in an earlier session Replied, post #78 · Evidence › Journal club · 13 Jul 2026 · 30 likes SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral formulation. Note that oral bioavailability is lower…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #39 · Practice › Side effects · 9 Jul 2026 · 31 likes Gallbladder complications: rapid weight loss increases the risk of gallstone formation. The mechanism is not specific to this drug class. The risk is greatest in the…
Submitting a sample: the process end to end Replied, post #53 · Sourcing › Independent verification · 2 Jul 2026 · 0 likes Coming back to post #51, because the follow-up matters more than the original answer. Cost and turnaround: different services have different pricing and turnaround…
Tracking a shortage from primary sources rather than rumour Replied, post #75 · Access › Shortages · 29 Jun 2026 · 4 likes post #74 answers the question as asked. The question underneath it is different. Resuming after a gap: after a gap of days or a few weeks, most people resume at the…
Tracking intake honestly when appetite is absent Replied, post #60 · Nutrition & Training › Protein & intake · 15 Jun 2026 · 0 likes Protein sources: animal sources (meat, fish, eggs, dairy) are denser and easier to hit targets with. Plant sources require higher volume. Neither is nutritionally…
Electrolyte supplements: which ones do anything Replied, post #27 · Nutrition & Training › Hydration & electrolytes · 10 Jun 2026 · 7 likes This follows post #24 rather than contradicting it. Magnesium: deficiency during weight loss is common and symptoms (fatigue, muscle cramps) are nonspecific.…
A reconstituted vial's beyond-use date and the reasoning behind common figures Replied, post #104 · Practice › Storage & stability · 9 Jun 2026 · 0 likes Vial integrity: once a vial is entered with a needle repeatedly, the rubber closure degrades and the integrity fails. Using the same vial repeatedly over weeks or…
Revisiting: Mean kinetic temperature explained without the mathematics Replied, post #57 · Practice › Storage & stability · 2 Jun 2026 · 23 likes Beyond-use dating: the date after which a prepared solution should not be used. It is an estimate based on how fast the solution degrades under stated storage, not on…
Personal or family history of medullary thyroid carcinoma — what changed since Replied, post #44 · Safety › Contraindications · 20 May 2026 · 14 likes Medullary thyroid carcinoma (personal or family history) or multiple endocrine neoplasia type 2: absolute contraindication. The rodent preclinical signal is real enough…
A comparison of home results against a laboratory result on the same vial — does this… Replied, post #4 · Analytics › Home & field testing · 10 May 2026 · 15 likes Colorimetric tests: colour intensity correlates with concentration, but the relationship is non-linear at extremes and the correlation depends on the exact conditions…
Pinch or no pinch, and how needle length changes the answer — the long version Replied, post #52 · Practice › Administration · 30 Apr 2026 · 6 likes post #51 answers the question as asked. The question underneath it is different. A genuinely late dose: the labelling generally says that if the next dose is more than…
A 40-week log with the measurement method stated — does this still hold? Replied, post #5 · Outcomes › Progress reports · 27 Apr 2026 · 1 like Longitudinal report with the method stated: same scale, same time of day, same conditions. A scale is a tool; use the same one each time. Consistency matters more than…
Why this subcategory is stricter about sourcing than most Replied, post #22 · Compounds › Secretagogues & GH axis · 25 Apr 2026 · 3 likes Secretagogues and glucose tolerance: there is a mechanistic concern that sustained growth hormone elevation might impair glucose tolerance. The clinical relevance of…
[2026 update] Regional warehouse stock versus direct despatch Replied, post #51 · Sourcing › Logistics · 24 Apr 2026 · 13 likes post #50 answers the question as asked. The question underneath it is different. Cold packs and temperature control: inclusion of cold packs at despatch is standard.…
Price changes over 2025 and 2026, tabulated and dated — does this still hold? Replied, post #157 · Access › Pricing · 24 Apr 2026 · 10 likes On post #153 — agreed on the reasoning, with one qualification. Subscription services and subscriptions: some online clinics bundle compounds into subscription models…
Foaming during reconstitution and whether it matters — the long version Replied, post #105 · Practice › Reconstitution · 20 Apr 2026 · 1 like This follows post #102 rather than contradicting it. Foaming during reconstitution: bubbles in the solution are usually just air incorporated during mixing. They…
Converting between mg/mL and units per dose, both directions — the long version Replied, post #25 · Practice › Reconstitution · 19 Apr 2026 · 0 likes On post #21 — agreed on the reasoning, with one qualification. Why "add 2 mL" is not an instruction: the powder in the vial takes up space. "Add 2 mL to a 10 mL vial"…
Journal club: SURMOUNT-4 and continuation versus withdrawal Replied, post #30 · Evidence › Journal club · 15 Apr 2026 · 6 likes Picking up post #27: that is the part I would want checked first. For anyone arriving from a search: the marked solution above is the direct answer, and the replies…
Anaesthesia and elective surgery: the aspiration question Replied, post #74 · Practice › Interactions · 4 Apr 2026 · 0 likes This follows post #71 rather than contradicting it. Supplements and herbs: many have no established interaction. Some do. If you are taking something unusual, checking…
Which panel is worth repeating and which is worth ignoring — a second dataset Replied, post #112 · Clinical › Bloodwork · 27 Mar 2026 · 0 likes Liver enzymes: elevation does not specify cause. ALT and AST can rise from many things. Bilirubin helps narrow down the cause. Multiple markers together are more…
Why "dose equivalence" between different incretin analogues is a weak concept Replied, post #3 · Practice › Dosing & titration · 14 Feb 2026 · 0 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Price changes over 2025 and 2026, tabulated and dated — does this still hold? Replied, post #85 · Access › Pricing · 10 Feb 2026 · 0 likes Coming back to post #83, because the follow-up matters more than the original answer. Cost per milligram is the only comparison that survives format differences, but…
Seven-day rolling means and why weekly readings mislead — one year on Replied, post #14 · Outcomes › Progress reports · 7 Feb 2026 · 0 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
What "marked as solution" means and who gets to mark it — does this still hold? Replied, post #34 · Start Here › Welcome · 23 Jan 2026 · 4 likes Welcome. The orientation materials are pinned at the top of this category and they take about an hour. They answer most of the questions a new member has and they save…
Preprint servers and what screening they do Replied, post #30 · Evidence › Preprints · 20 Jan 2026 · 3 likes Picking up post #27: that is the part I would want checked first. Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes…
Why a compound being unapproved is not the same as being illegal to possess Replied, post #51 · Sourcing › Regulatory · 19 Jan 2026 · 0 likes post #50 is right about the mechanism and I think understates the practical bit. Approval versus licensing: a compound can be approved for a specific indication in one…
Warfarin and altered intake: the monitoring argument — the long version Replied, post #86 · Practice › Interactions · 9 Jan 2026 · 0 likes On post #82 — agreed on the reasoning, with one qualification. Vitamins: most vitamins have no significant interaction. Fat-soluble vitamins (A, D, E, K) might be…
A partial dose because the pen emptied mid-injection Replied, post #35 · Practice › Administration · 8 Jan 2026 · 17 likes Drawing up with one needle and injecting with another: a reasonable practice if you have extra needles. Fresh needle for injection reduces tissue drag and can decrease…
Second pass at: The topic list is dense — is that deliberate? Replied, post #26 · Meta › Site feedback · 23 Dec 2025 · 10 likes post #25 answers the question as asked. The question underneath it is different. Community norms: if you think a norm has drifted or is not being followed consistently,…
Second pass at: Adsorptive losses at low concentration, and why dilute solutions are… Replied, post #4 · Practice › Storage & stability · 20 Dec 2025 · 0 likes Worth separating two things that post #3 runs together. Container choice matters: the material of the vial, the rubber closure, the fill volume all affect how quickly…
Tracking a preprint to publication: a worked example Replied, post #114 · Evidence › Preprints · 11 Dec 2025 · 1 like post #113 is right about the mechanism and I think understates the practical bit. Thank you for the correction. I have edited my earlier post with a note rather than…
Persistent vomiting and the threshold for seeking help Replied, post #78 · Safety › Adverse events · 29 Nov 2025 · 0 likes post #77 is right about the mechanism and I think understates the practical bit. How to document: date, exact symptom or event, severity, duration, outcome, any medical…
Revisiting: Review: an evidence digest and the citation check that delayed it Replied, post #33 · Documentation › Doc review · 24 Nov 2025 · 27 likes Interdependencies: if updating one page requires updating related pages, posting that connection here helps the maintainers see the scope of work.
Long-time reader, first-time poster Replied, post #19 · Lounge › Introductions · 17 Nov 2025 · 3 likes Worth separating two things that post #15 runs together. Lurking first: if you want to introduce yourself after lurking a bit, that is fine. You do not have to…
Pen dose counters: what a click does and does not guarantee Replied, post #36 · Devices › Pens & autoinjectors · 14 Nov 2025 · 3 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
What a purity-only report leaves out Replied, post #86 · Sourcing › Independent verification · 14 Nov 2025 · 0 likes On post #82 — agreed on the reasoning, with one qualification. Medutest: combined purity and identity reporting. Appears throughout vendor documentation. Where a…
Half-life, steady state, and accumulation worked through — a second dataset Replied, post #16 · Pharmacology › Pharmacokinetics · 9 Nov 2025 · 20 likes Half-life: semaglutide ≈ 165–184 hours (about a week). Tirzepatide ≈ 5 days. Liraglutide ≈ 13 hours. The half-life determines how much accumulation happens at steady…
Why oral semaglutide needs an absorption enhancer at all Replied, post #45 · Compounds › Oral incretins · 28 Oct 2025 · 0 likes PIONEER programme is phase 3 for oral semaglutide. The trials cover multiple indications and durations. Reading them requires attention to which trial is which because…
What happens after your first post: likes, trust levels, and why none of it matters much… Replied, post #89 · Start Here › Welcome · 21 Oct 2025 · 0 likes Trust levels accumulate over time and they give you access to small things like the ability to edit your own posts without a timestamp. They are not a status symbol and…
Hypertension improvement and when medication needs revisiting Replied, post #64 · Clinical › Comorbidities · 16 Sep 2025 · 7 likes Picking up post #61: that is the part I would want checked first. Comorbidity control: if a comorbidity (high blood pressure, high lipids) is not adequately controlled,…
Documentation that appears only after payment Replied, post #25 · Sourcing › Red flags · 15 Sep 2025 · 27 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Aggregated purity results across four services, with caveats — a second dataset Replied, post #18 · Data & Tools › Datasets · 7 Sep 2025 · 26 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
Thyroid function tests during substantial weight change Replied, post #49 · Clinical › Bloodwork · 2 Sep 2025 · 20 likes post #48 is right about the mechanism and I think understates the practical bit. Lipid panel interpretation: total, LDL, HDL, triglycerides all on one panel. Reading…
Coming back to: Why quantitation is the hard part, not detection Replied, post #58 · Analytics › Home & field testing · 30 Aug 2025 · 11 likes Precision of home tests: most consumer-accessible devices are not precise to the level people want ("is this 99% pure or 97% pure"). They give a yes/no or a rough…
Are there stupid questions here? A staff answer, at length Replied, post #130 · Start Here › Welcome · 30 Aug 2025 · 6 likes Coming back to post #128, because the follow-up matters more than the original answer. Off-topic posts that do not belong here belong in the Lounge instead. You are not…
A parcel that arrived warm: a decision process, not a verdict Replied, post #14 · Practice › Storage & stability · 26 Aug 2025 · 31 likes Dating prepared solutions: write the date reconstitution on the vial in permanent marker. If you later need to know whether it has been sitting for weeks or days, the…
Second pass at: What "verified" means on our vendor pages, stated narrowly Replied, post #9 · Sourcing › Vendor reports · 22 Aug 2025 · 0 likes Coming back to post #7, because the follow-up matters more than the original answer. Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if…
Follow-up: The decimal-point error, and the habit that catches it Replied, post #42 · Practice › Reconstitution · 15 Aug 2025 · 2 likes Swirling versus inverting versus leaving it alone: the vial can be gently warmed (hands around it) and swirled with a rolling motion. Vigorous shaking introduces air…
Second pass at: Why this subcategory is stricter about sourcing than most Replied, post #64 · Compounds › Secretagogues & GH axis · 14 Aug 2025 · 0 likes Pulsatile secretion matters because growth hormone is secreted in pulses, not continuously. A single post-dose growth hormone level is nearly uninterpretable. Assessing…
Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly Replied, post #163 · Compounds › Tirzepatide · 12 Aug 2025 · 3 likes The GIP component: GIP receptor agonism is thought to amplify the GLP-1 effect on satiety and energy expenditure, but how much of tirzepatide's effect is that and how…
Are there stupid questions here? A staff answer, at length Replied, post #57 · Start Here › Welcome · 10 Aug 2025 · 2 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Travel coolers and how long they really hold Replied, post #54 · Devices › Cold chain · 5 Aug 2025 · 0 likes This follows post #51 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
Follow-up: Why we hide unevidenced fraud accusations and log the hiding Replied, post #15 · Sourcing › Red flags · 1 Aug 2025 · 20 likes Inability to trace lots: if you ask "where was this synthesised, by whom, under what conditions" and cannot get a clear answer, that is a red flag. Traceability is not…
Revisiting: GLP-1 receptor distribution: central and peripheral Replied, post #22 · Pharmacology › Receptor biology · 1 Aug 2025 · 19 likes This follows post #19 rather than contradicting it. For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add…
Titles that describe the question, not the situation Replied, post #55 · Start Here › How to Ask · 24 Jul 2025 · 26 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
Coming back to: Cross-border purchase rules within the EU Replied, post #13 · Regional › European Union · 20 Jul 2025 · 0 likes Spain: AEMPS is the regulator. Public reimbursement for weight management has been limited with regional variation in specialist pathways. Private prescription is common.
Coming back to: Nausea profile of amylin analogues compared with GLP-1 agonists Replied, post #22 · Compounds › Cagrilintide & amylin analogues · 7 Jul 2025 · 0 likes I read post #20 twice before replying, because I had assumed the opposite. Two things before anyone answers the substance. First, the context in the first post is clear…
Why fasting instructions for oral semaglutide are not optional advice — does this still… Replied, post #55 · Compounds › Oral incretins · 28 Jun 2025 · 0 likes Worth separating two things that post #51 runs together. PIONEER programme is phase 3 for oral semaglutide. The trials cover multiple indications and durations. Reading…
Revisiting: Reading a denial letter as a specification for your appeal Replied, post #20 · Access › Insurance & coverage · 20 Jun 2025 · 0 likes Prior authorisation: pre-approval requirements and how to satisfy them. Most denials cite specific criteria. Understanding the criterion is the first step in satisfying…
Journal club: SURMOUNT-1, read without the press release Replied, post #138 · Evidence › Journal club · 15 Jun 2025 · 4 likes PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not efficacy. Non-inferiority for safety was met. The trial was not designed to…
An emergency department visit, described afterwards Replied, post #31 · Safety › Adverse events · 15 Jun 2025 · 0 likes Picking up post #28: that is the part I would want checked first. Allergic reactions: true allergy (anaphylaxis, severe rash) is rare with these peptide compounds but…
[2026 update] An appeal that failed, and what I would do differently Replied, post #88 · Access › Insurance & coverage · 13 Jun 2025 · 4 likes Prior authorisation: pre-approval requirements and how to satisfy them. Most denials cite specific criteria. Understanding the criterion is the first step in satisfying…
A supplier that answers analytical questions with restated claims Replied, post #87 · Sourcing › Red flags · 31 May 2025 · 17 likes Safety documentation absent: a supplier that cannot provide information about sterility testing, endotoxin testing, or safety documentation when asked is raising flags.
TB-500 and thymosin beta-4: the fragment versus the protein Replied, post #25 · Compounds › Repair & healing peptides · 28 May 2025 · 18 likes Reading a preclinical wound-healing model: the model shows whether a mechanism is plausible in a specific context. It does not show magnitude of effect in humans, does…
Requesting a translation of an existing page Replied, post #20 · Documentation › Wiki requests · 23 May 2025 · 0 likes Coming back to post #18, because the follow-up matters more than the original answer. Translation suggestions: if a maintained page should exist in another language,…
Pregnancy as an absolute contraindication Replied, post #103 · Safety › Contraindications · 21 May 2025 · 0 likes post #102 answers the question as asked. The question underneath it is different. Diabetic retinopathy complications: a signal for this was noted in SUSTAIN 6. Current…
Follow-up: What other technical communities get right that we do not Replied, post #98 · Lounge › Off topic · 15 May 2025 · 6 likes I read post #96 twice before replying, because I had assumed the opposite. Science communication: if you come across an interesting science paper or article about…
Publishing an inconvenient result: a case study Replied, post #17 · Sourcing › Independent verification · 8 May 2025 · 2 likes Cost and turnaround: different services have different pricing and turnaround times. Janoshik's turnaround is weeks by mail; VendorInvestigate documentation review is…
How Janoshik, Medutest, PeptideMeter and VendorInvestigate differ Replied, post #46 · Sourcing › Independent verification · 4 May 2025 · 16 likes Picking up post #43: that is the part I would want checked first. I disagree with the reply above, and I think the disagreement is substantive rather than…
Follow-up: Documentation that appears only after payment Replied, post #40 · Sourcing › Red flags · 2 May 2025 · 31 likes post #39 is right about the mechanism and I think understates the practical bit. Evasion when asked: if a supplier does not clarify when asked specifically for method…
[2026 update] Cardiovascular risk: reading the outcome trials as a set Replied, post #26 · Clinical › Comorbidities · 1 May 2025 · 9 likes Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and SUSTAIN programmes established glycaemic benefit. The renal and…
Follow-up: Documentation that appears only after payment Replied, post #2 · Sourcing › Red flags · 15 Apr 2025 · 3 likes Worth separating two things that the opening post runs together. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly…
Scheduled maintenance and what will be unavailable Replied, post #92 · Meta › Announcements · 31 Mar 2025 · 4 likes Worth separating two things that post #88 runs together. Feedback to announcements: if you have feedback on an announced change (not a question, but your position) post…
Semaglutide half-life: where the 165 to 184 hour figure comes from — what changed since Replied, post #130 · Compounds › Semaglutide · 17 Mar 2025 · 6 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly Replied, post #39 · Compounds › Tirzepatide · 14 Mar 2025 · 0 likes Dual agonism versus dose: how much of tirzepatide's effect is the GIP component and how much is simply achieving higher receptor engagement? The honest answer is that…
Why plausible mechanism is not evidence of effect Started this topic · Compounds › Repair & healing peptides · 8 Mar 2025 · 23 likes Asking directly, because I could not find a straight answer: Why plausible mechanism is not evidence of effect Session topic: STEP 2 ( Lancet , 2021). Please read it…
Pharmaceutical compounding rules, summarised from primary sources Replied, post #156 · Sourcing › Regulatory · 6 Mar 2025 · 5 likes post #155 is right about the mechanism and I think understates the practical bit. Labelling and intended use: a compound sold as "research-use-only" does not change its…
Pharmaceutical compounding rules, summarised from primary sources Replied, post #116 · Sourcing › Regulatory · 4 Mar 2025 · 27 likes Compounding and pharmacy rules: some jurisdictions allow a pharmacy to compound a drug that is not on the market under specific conditions. The conditions are strict…
Assessing a warm arrival: the decision process Started this topic · Sourcing › Logistics · 6 Feb 2025 · 15 likes Posting this under the heading it deserves: Assessing a warm arrival: the decision process Everything below is what sits behind that. A logistics question, since the…
What we do not know about retatrutide, listed explicitly Replied, post #73 · Compounds › Retatrutide · 28 Jan 2025 · 0 likes Triple agonism: is the effect additive, synergistic, or neither? A phase 2 comparison of tirzepatide (dual) to retatrutide (triple) would answer that question. The…
Research-use-only status: what it means legally and practically — a second dataset Replied, post #68 · Compounds › Other compounds · 20 Jan 2025 · 6 likes post #67 answers the question as asked. The question underneath it is different. Distinguishing marketed research compounds from true chemical synthesis: some online…
Fixed versus detachable needles: the trade-offs Replied, post #121 · Devices › Syringes & needles · 18 Jan 2025 · 0 likes I read post #119 twice before replying, because I had assumed the opposite. Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume…
Building a sensible monitoring schedule with your prescriber Replied, post #27 · Clinical › Bloodwork · 19 Dec 2024 · 3 likes Lipid panel interpretation: total, LDL, HDL, triglycerides all on one panel. Reading them together is more informative than reading one value in isolation. An elevated…
Two sessions a week versus four: what the evidence supports Replied, post #32 · Nutrition & Training › Resistance training · 12 Dec 2024 · 9 likes This follows post #29 rather than contradicting it. Intensity: using weights that allow 6 to 12 reps before fatigue is a reasonable range for preserving muscle. Heavier…
Why "any advice?" is the least effective ending for a post Replied, post #94 · Start Here › How to Ask · 1 Dec 2024 · 30 likes Five questions in one post gets you one answer: the easiest one, usually not the one you needed most. Post them separately or pick the one that depends on the others…
Revisiting: Moderation log format change Replied, post #21 · Meta › Announcements · 9 Nov 2024 · 12 likes Staff-only posts: some announcements are visible only to staff (concerning internal operations). Members see public announcements.
Hypertension improvement and when medication needs revisiting — a second dataset Replied, post #127 · Clinical › Comorbidities · 29 Oct 2024 · 14 likes Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and SUSTAIN programmes established glycaemic benefit. The renal and…
Requesting a page: what makes a good request — what changed since Replied, post #124 · Documentation › Wiki requests · 13 Oct 2024 · 0 likes post #123 is right about the mechanism and I think understates the practical bit. Flag a page that has drifted: if you notice a maintained page has information that is…
Progressive overload when the scale is falling — one year on Replied, post #15 · Nutrition & Training › Resistance training · 30 Aug 2024 · 3 likes Volume: the number of sets per muscle group per week that supports muscle maintenance is roughly 12 to 18 hard sets. That varies by individual but gives a target range.
Correlation in a self-tracked dataset: what it can support Replied, post #27 · Research Methods › Statistics · 21 Aug 2024 · 3 likes Absence of evidence and evidence of absence: if a study is small and finds no effect, that is absence of evidence, not evidence of absence. A larger study might find an…
Reading a meta-analysis you disagree with, fairly Replied, post #9 · Evidence › Meta-analyses · 6 Aug 2024 · 0 likes Why forest plots are more informative than pooled numbers: they show the variation across studies, which tells you whether the effect is consistent or heterogeneous. A…
The mass-error checker and its intended scope Replied, post #142 · Data & Tools › Calculators · 21 Jul 2024 · 7 likes Worth separating two things that post #138 runs together. Titration planning: a calculator that shows you the escalation schedule for different starting and ending…
Pen wastage and its effect on real cost Replied, post #3 · Access › Pricing · 22 Jun 2024 · 10 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Assessing a warm arrival: the decision process — one year on Replied, post #136 · Sourcing › Logistics · 2 Jun 2024 · 29 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.