i.broberg

TL2 Moderator · Bari

Contributes reviews on supplier material. Based in Bari.

Joined 9 February 2025 · last posted 4d

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Journal club: what we got wrong in an earlier session Replied, post #117 · Evidence › Journal club · 24 Jul 2026 · 16 likes TRIUMPH (ongoing): Retatrutide phase 3. No results yet. Nothing should be attributed to it because it has not finished. When it does, this discussion will return to it.
Revisiting: Protein density versus volume when you cannot eat much Replied, post #85 · Nutrition & Training › Protein & intake · 20 Jul 2026 · 0 likes Protein targets during weight loss: the standard recommendation is 1.6 to 2.2 grams per kilogram of body weight. Individual requirements vary but that range is a…
NHS criteria and how they are applied in practice Replied, post #32 · Regional › UK & Ireland · 17 Jul 2026 · 4 likes Worth separating two things that post #28 runs together. MHRA is the regulator. Licensed incretin analogues are prescription-only medicines. NHS and private prescribing…
Revisiting: What pooling buys you and what it destroys Replied, post #93 · Evidence › Meta-analyses · 16 Jul 2026 · 3 likes When a meta-analysis is unhelpful: if the included studies are heterogeneous in population, intervention, or outcome, pooling them produces a number that represents…
[2026 update] Regional warehouse stock versus direct despatch Replied, post #135 · Sourcing › Logistics · 15 Jul 2026 · 1 like Declaring contents accurately: declaring accurately reduces intervention risk. A declaration of "peptide research chemical, 5 grams" is better than "vitamin" or "other"…
Documenting a supplier's response to a discrepancy Replied, post #38 · Sourcing › Vendor reports · 14 Jul 2026 · 11 likes post #37 answers the question as asked. The question underneath it is different. Blind submission is worth the effort: have someone else relabel the sample so neither…
Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #24 · Evidence › Meta-analyses · 9 Jul 2026 · 26 likes Worth separating two things that post #20 runs together. Number needed to treat from a meta-analysis: can be computed from the pooled estimate if the baseline risk is…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #88 · Evidence › Journal club · 7 Jul 2026 · 22 likes This follows post #85 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
What other technical communities get right that we do not Replied, post #6 · Lounge › Off topic · 6 Jul 2026 · 15 likes Worth separating two things that post #2 runs together. Humour: light, relevant humour is welcome. Cruel humour targeting individuals or groups is not.
[2026 update] Area percent versus weight percent: the confusion that causes most arguments Replied, post #67 · Analytics › HPLC & UHPLC · 4 Jul 2026 · 6 likes This is why a purity figure without the underlying chromatogram is weaker evidence than it appears. It is also why two competent laboratories can report different…
Pooling trials with different estimands Replied, post #55 · Evidence › Meta-analyses · 28 Jun 2026 · 30 likes Worth separating two things that post #51 runs together. Inclusion and exclusion criteria: a meta-analysis is only as good as its inclusion criteria. If the criteria…
Does dual agonism explain the effect size, or is it dose? Replied, post #59 · Compounds › Tirzepatide · 25 Jun 2026 · 20 likes SURMOUNT-OSA is notable because it used an objective physiological endpoint, the apnoea-hypopnoea index, rather than a symptom scale. Two parallel trials, with and…