Ranked by engagement

Top topics — this month page 3

Ranked by replies, likes and views over this month, with a bonus for topics that reached a marked solution. Engagement is a proxy for usefulness and a poor one; the documentation commons is the better index of what is settled.

This week This month This quarter This year All time

374 topics · page 3 of 13

Topic	Participants	Replies	Views	Activity
Constipation management, with a dietitian's contribution Practice › Side effects constipation nausea delayed gastric emptying vomiting Solved Posting this under the heading it deserves: Constipation management, with a dietitian's contribution Everything below is what sits behind that. Practical question with the units stated, because I have seen…	+79	88	27k	21d
A supplier who responds to a discrepancy with silence — what changed since Sourcing › Red flags mislabelling disputed documentation quality underdosing Wiki A supplier who responds to a discrepancy with silence — what changed since — setting out what I have, and where I think it stops being reliable. A logistics question, since the answers here are usually better…	+83	88	21k	6h
Second pass at: Sleep apnoea improving and the equipment implications Wellbeing › Sleep fatigue heart rate obstructive sleep apnoea On the subject in the title: Second pass at: Sleep apnoea improving and the equipment implications Working notes rather than a conclusion. General question, not a request for advice about my own care — I know…	+89	96	1.1k	10h
Stability of BPC-157 in solution: what has been measured — one year on Compounds › Repair & healing peptides needs a source observational data preprint BPC-157 On the subject in the title: Stability of BPC-157 in solution: what has been measured — one year on Working notes rather than a conclusion. Comparing STEP 2 ( Lancet , 2021) with STEP 1 ( N Engl J Med , 2021)…	+84	98	7.8k	18h
Follow-up: Prior authorisation: what the criteria usually require Access › Insurance & coverage insurance appeals formulary prior authorisation Solved Prior authorisation: what the criteria usually require — setting out what I have, and where I think it stops being reliable. A coverage question with the paperwork detail included, since that is what…	+95	100	9.1k	10h
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Practice › Side effects constipation delayed gastric emptying fatigue hair shedding Solved Posting this under the heading it deserves: Muscle cramps: the ordinary causes before the exotic ones — a second dataset Everything below is what sits behind that. Reporting something rather than asking about…	+65	77	39k	1d
[2026 update] Travelling with an injectable: documentation and practicalities Access › International telehealth EMA MHRA NHS Travelling with an injectable: documentation and practicalities Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because everything in…	+107	111	12k	1d
Why retatrutide discussion here is more cautious than elsewhere — one year on Compounds › Retatrutide TRIUMPH programme effect size preprint retatrutide Asking directly, because I could not find a straight answer: Why retatrutide discussion here is more cautious than elsewhere — one year on Session topic: PIONEER 6 ( N Engl J Med , 2019). Please read it…	+92	97	3.6k	20h
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Analytics › Home & field testing third-party testing LOD & LOQ documentation quality ELISA Solved On the subject in the title: Lateral-flow and colorimetric approaches: the specificity problem Working notes rather than a conclusion. I would like to understand what this number means before I repeat it…	+77	89	16k	9h
The most useful thing you learned here that was not the answer you came for Lounge › Off topic long read beginner friendly The most useful thing you learned here that was not the answer you came for Writing it up because I had to work it out twice and would rather nobody else did. Lower-stakes topic, but the sourcing rule still…	+54	61	57k	1d
Endotoxin and why it is a separate question from purity — what changed since Analytics › Impurities & related substances HPLC endotoxin testing data table forced degradation On the subject in the title: Endotoxin and why it is a separate question from purity — what changed since Working notes rather than a conclusion. A documentation question rather than an analytical one. I have…	+78	91	1k	10h
Revisiting: Protein density versus volume when you cannot eat much Nutrition & Training › Protein & intake constipation micronutrients lean mass loss fatigue Revisiting: Protein density versus volume when you cannot eat much Writing it up because I had to work it out twice and would rather nobody else did. Longitudinal report with the method stated, because a…	+97	108	3.6k	2d
Personal or family history of medullary thyroid carcinoma — what changed since Safety › Contraindications pancreatitis thyroid C-cell question delayed gastric emptying Posting this under the heading it deserves: Personal or family history of medullary thyroid carcinoma — what changed since Everything below is what sits behind that. Asking about a population rather than…	+91	96	1.3k	25d
Asking a follow-up: new topic or new reply? Start Here › How to Ask worked example onboarding beginner friendly Solved Asking a follow-up: new topic or new reply? — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title. Context below, and I have tried to include the…	+68	73	40k	1d
A widely repeated interaction claim that turns out to be unsupported — what changed since Practice › Interactions insulin hypoglycaemia metformin needs a source Solved A widely repeated interaction claim that turns out to be unsupported — what changed since Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on…	+89	94	5.9k	2h
Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with real criteria Analytics › Method validation linearity recovery precision & repeatability system suitability On the subject in the title: Specificity, linearity, accuracy, precision, range, robustness — with real criteria Working notes rather than a conclusion. Posting the method first, because I know what the first…	+93	99	1.4k	6d
Hair shedding at month three: mechanism and time course — the long version Practice › Side effects nausea delayed gastric emptying vomiting Hair shedding at month three: mechanism and time course — the long version Writing it up because I had to work it out twice and would rather nobody else did. Reporting something rather than asking about it,…	+50	54	50k	1d
Reading a rodent study on a secretagogue without over-extrapolating — the long version Compounds › Secretagogues & GH axis observational data tesamorelin ipamorelin needs a source Reading a rodent study on a secretagogue without over-extrapolating — the long version — setting out what I have, and where I think it stops being reliable. I have seen STEP 4 ( JAMA , 2021) cited in support…	+59	66	30k	4h
An 18-month record including the parts that went badly Outcomes › Progress reports data table long read effect size DXA An 18-month record including the parts that went badly — setting out what I have, and where I think it stops being reliable. Longitudinal report with the method stated, because a number without a method is…	+77	81	17k	12h
Reflectance and photometric devices: precision in practice — a second dataset Analytics › Home & field testing ELISA LOD & LOQ documentation quality Reflectance and photometric devices: precision in practice — a second dataset — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I…	+75	82	17k	12h
Fasting versus non-fasting and which tests care Clinical › Bloodwork eGFR & renal function lipase & amylase HbA1c Solved Fasting versus non-fasting and which tests care Writing it up because I had to work it out twice and would rather nobody else did. General question, not a request for advice about my own care — I know the…	+72	78	14k	19h
Follow-up: Sleep quality changes during weight loss Wellbeing › Sleep fatigue obstructive sleep apnoea heart rate On the subject in the title: Sleep quality changes during weight loss Working notes rather than a conclusion. General question, not a request for advice about my own care — I know the difference and I would…	+74	80	4.4k	14h
Pages past their review date, listed — does this still hold? Meta › Wiki maintenance review date moderation maintainership wiki post Asking directly, because I could not find a straight answer: Pages past their review date, listed — does this still hold? Nominating something for promotion into the documentation commons. The topic in…	+49	56	39k	11d
Why the timeline is on the right and not the left — what changed since Meta › Site feedback site feedback moderation guidelines Solved Why the timeline is on the right and not the left — what changed since I have a specific reason for asking rather than idle curiosity, and the context is below. Nominating something for promotion into the…	+77	81	4k	2d
How to ask a question when you cannot say why you are asking it Start Here › How to Ask beginner friendly site feedback worked example onboarding Solved Asking directly, because I could not find a straight answer: How to ask a question when you cannot say why you are asking it Question in the title. Context below, and I have tried to include the things people…	+49	53	36k	4h
Primary endpoint hierarchies and why order matters — one year on Evidence › Trials surrogate endpoints discontinuation & dropout estimand randomised trial Solved On the subject in the title: Primary endpoint hierarchies and why order matters — one year on Working notes rather than a conclusion. Comparing SELECT ( N Engl J Med , 2023) with SURPASS-2 ( N Engl J Med ,…	+56	61	37k	11h
Comparing my trajectory with the trial curves, carefully — a second dataset Outcomes › Progress reports effect size data table long read Comparing my trajectory with the trial curves, carefully — a second dataset — setting out what I have, and where I think it stops being reliable. Maintenance rather than loss, which is the part of this that…	+77	81	16k	11h
Revisiting: Liver enzymes drifting down and what that usually means Clinical › Bloodwork thyroid function eGFR & renal function liver enzymes lipase & amylase On the subject in the title: Revisiting: Liver enzymes drifting down and what that usually means Working notes rather than a conclusion. General question, not a request for advice about my own care — I know…	+55	61	39k	3h
Designing a personal experiment that could change your mind — one year on Research Methods › N-of-1 designs effect size data table worked example Designing a personal experiment that could change your mind — one year on — setting out what I have, and where I think it stops being reliable. Session topic: STEP 4 ( JAMA , 2021). Please read it before…	+74	80	17k	2d
What to bring: records that a clinician can actually use — a second dataset Clinical › Prescriber conversations telehealth beginner friendly prior authorisation What to bring: records that a clinician can actually use — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about a population rather than…	+80	86	5.6k	3h