t.dumitru

TL2 Moderator · Rosario

Contributes reviews on supplier material. Based in Rosario.

Joined 3 October 2024 · last posted 7d

97 posts, newest first. Showing up to 150.

Forced degradation studies: designing one that is informative Replied, post #103 · Analytics › Method validation · 21 Jul 2026 · 1 like Limits of detection and quantitation: LOD is the lowest concentration that produces a signal above background. LOQ is the lowest concentration at which the method meets…
A structured critique template this community uses — a second dataset Replied, post #42 · Evidence › Study critique · 18 Jul 2026 · 11 likes Coming back to post #40, because the follow-up matters more than the original answer. Confounding: in observational data, is there a third variable that explains the…
What consumer-accessible tests can and cannot determine — a second dataset Replied, post #60 · Analytics › Home & field testing · 7 Jul 2026 · 31 likes Worth separating two things that post #56 runs together. Why third-party testing is stronger: a home test run by the person who made the compound is a self-selected…
Micro-titration: a disputed topic, argued properly — one year on Replied, post #58 · Practice › Dosing & titration · 3 Jul 2026 · 12 likes post #57 answers the question as asked. The question underneath it is different. Thank you for the correction. I have edited my earlier post with a note rather than…
Angle of injection and whether 90 degrees is always right — the long version Replied, post #35 · Practice › Administration · 30 Jun 2026 · 5 likes Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose.…
Secretagogues and glucose tolerance: the mechanistic concern Replied, post #55 · Compounds › Secretagogues & GH axis · 30 Jun 2026 · 23 likes On post #51 — agreed on the reasoning, with one qualification. Pulsatile secretion matters because growth hormone is secreted in pulses, not continuously. A single…
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Replied, post #36 · Analytics › Method validation · 28 Jun 2026 · 0 likes Forced degradation studies: deliberately stress the material with acid, base, oxidant, heat, light to generate degradation products and demonstrate that the method can…
Publication patterns in the BPC-157 literature, examined Replied, post #23 · Compounds › Repair & healing peptides · 28 Jun 2026 · 20 likes Stability of BPC-157 in solution: what has been measured in published work covers specific formulations under specific conditions. Extrapolating to a reconstituted…
Manufacturer assistance programmes and their eligibility rules Replied, post #37 · Access › Pricing · 26 Jun 2026 · 14 likes On post #33 — agreed on the reasoning, with one qualification. Cost per milligram is the only comparison that survives format differences, but even then it needs care.…
Revisiting: Theoretical plates: useful number or ritual? Replied, post #12 · Analytics › HPLC & UHPLC · 9 Jun 2026 · 0 likes post #11 answers the question as asked. The question underneath it is different. Reversed-phase separates on hydrophobicity. A peptide is retained on a non-polar…
Racemisation and why it is invisible to a mass measurement Replied, post #23 · Analytics › Impurities & related substances · 9 Jun 2026 · 0 likes post #22 is right about the mechanism and I think understates the practical bit. Related substances: compounds chemically related to the target peptide but not the…
An 18-month record including the parts that went badly Replied, post #28 · Outcomes › Progress reports · 30 May 2026 · 27 likes Rate of change: reporting progress as "lost 5 kg in 12 weeks" is more useful than "currently at 82 kg" because the rate tells you whether the change is steady,…
Purity assay versus content assay: two different numbers Replied, post #2 · Analytics › COA interpretation · 25 May 2026 · 0 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Spreadsheets: an appreciation — what changed since Replied, post #51 · Lounge › Off topic · 24 May 2026 · 25 likes This follows post #48 rather than contradicting it. Personal stories: if you want to talk about what led you to this compound, your journey, or how the change has…
Alcohol: what is documented and what is folklore Replied, post #18 · Practice › Interactions · 19 May 2026 · 30 likes post #17 answers the question as asked. The question underneath it is different. Insulin interaction: semaglutide and tirzepatide are not contraindicated with insulin…
Injection volume, overload, and peak distortion Replied, post #9 · Analytics › HPLC & UHPLC · 16 May 2026 · 29 likes post #8 is right about the mechanism and I think understates the practical bit. Method validation is the demonstration that a method can separate the compound from its…
Tracking intake honestly when appetite is absent Replied, post #21 · Nutrition & Training › Protein & intake · 10 May 2026 · 3 likes post #20 answers the question as asked. The question underneath it is different. Protein targets during weight loss: the standard recommendation is 1.6 to 2.2 grams per…
Request: show the solution author in the topic list — what changed since Replied, post #78 · Meta › Feature requests · 4 May 2026 · 1 like Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Journal club: indirect comparison between two programmes, defended and attacked Replied, post #46 · Evidence › Journal club · 2 May 2026 · 22 likes This follows post #43 rather than contradicting it. Critical appraisal template: (1) What did the trial set out to estimate? (2) Could the design answer that question?…
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #59 · Sourcing › Vendor reports · 30 Apr 2026 · 12 likes Lot matching: confirm the lot number on the certificate matches the lot number on the vial. A result from a different lot is not evidence about your vial.
Blind submission and why it changes minds — the long version Replied, post #46 · Sourcing › Independent verification · 28 Apr 2026 · 13 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #22 · Devices › Syringes & needles · 23 Apr 2026 · 0 likes Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on…
[2026 update] A vial that will not fully dissolve: what to check and in what order Replied, post #19 · Practice › Reconstitution · 21 Apr 2026 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #13 · Practice › Reconstitution · 12 Apr 2026 · 33 likes Choosing a concentration on purpose rather than by accident: starting with "I want to draw 0.5 mL per dose" and working backward to the required concentration is more…
Coming back to: Training through a dose escalation week Replied, post #55 · Nutrition & Training › Resistance training · 18 Mar 2026 · 0 likes Deload weeks: periodic weeks (every 4 to 8 weeks) with reduced volume and intensity can help with recovery and sometimes reveal strength gains that got obscured by…
Introducing myself: pharmacist, sceptic, reluctant participant — one year on Replied, post #77 · Lounge › Introductions · 15 Mar 2026 · 0 likes I read post #75 twice before replying, because I had assumed the opposite. Say hello. No question required. Introduce yourself if you want to give context for why you…
Nausea profile of amylin analogues compared with GLP-1 agonists Replied, post #64 · Compounds › Cagrilintide & amylin analogues · 14 Mar 2026 · 0 likes Cagrilintide alone is discussed less than in combination because the published data is almost entirely from combination trials. The phase 2 combination data was…
Reading a preclinical wound-healing model and its relevance to a human tendon — a second… Replied, post #27 · Compounds › Repair & healing peptides · 10 Mar 2026 · 18 likes BPC-157: the preclinical literature is extensive, mostly from a small number of research groups, and reports effects across a wide range of injury models. The breadth…
Why the titration planner refuses to produce a schedule below a floor Replied, post #45 · Data & Tools › Calculators · 3 Mar 2026 · 17 likes Mass error checking: enter your observed mass and theoretical mass and check whether the difference in ppm is within reasonable bounds for your instrument. Useful…
Measurement error in a self-reported exposure Replied, post #54 · Evidence › Study critique · 24 Feb 2026 · 3 likes Choosing the worst interpretation: "The confidence interval includes a harmful effect" is true if the CI goes from -1 to +5. But assuming the worst-case scenario is not…
The most common factual error about semaglutide on the internet — what changed since Replied, post #34 · Compounds › Semaglutide · 24 Feb 2026 · 2 likes The C-cell question: semaglutide triggered medullary thyroid carcinoma in rodent toxicology studies. A signal in rodents does not automatically appear in humans, but it…
Second pass at: Identical chromatograms across two different lots Replied, post #23 · Sourcing › Red flags · 23 Feb 2026 · 0 likes post #22 answers the question as asked. The question underneath it is different. Exaggerated claims without documentation: every compound has limits. No peptide is…
Revisiting: Absolute versus relative contraindications Replied, post #29 · Safety › Contraindications · 21 Feb 2026 · 8 likes I read post #27 twice before replying, because I had assumed the opposite. Having read the exchange above, I think I was wrong earlier in this topic and I want to say…
Blinding yourself: practical methods and their limits Replied, post #6 · Research Methods › N-of-1 designs · 19 Feb 2026 · 24 likes Blinding: blinding yourself (not knowing which condition you are in) removes expectation bias. This is hard to do with these compounds (the appetite suppression is hard…
Revisiting: Journal club: SURMOUNT-1, read without the press release Replied, post #13 · Evidence › Journal club · 30 Jan 2026 · 0 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Second pass at: Adsorptive losses at low concentration, and why dilute solutions are… Replied, post #24 · Practice › Storage & stability · 23 Jan 2026 · 0 likes Dating prepared solutions: write the date reconstitution on the vial in permanent marker. If you later need to know whether it has been sitting for weeks or days, the…
Non-inferiority margins: how they are chosen and how they are abused Replied, post #36 · Evidence › Trials · 17 Jan 2026 · 1 like post #35 answers the question as asked. The question underneath it is different. Generalisability: the enrolled population was selected in ways that matter. Entry…
Distinguishing expected GI effects from something that needs urgent attention Replied, post #90 · Practice › Side effects · 13 Jan 2026 · 0 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
Filter needles: when they help and what they cost you Replied, post #18 · Devices › Syringes & needles · 4 Jan 2026 · 2 likes Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a…
Tracking that stops updating and then resumes — the long version Replied, post #56 · Sourcing › Logistics · 25 Dec 2025 · 7 likes Coming back to post #54, because the follow-up matters more than the original answer. Reshipment after seizure: if a parcel is seized, some suppliers will reship;…
Oral versus injectable exposure: comparing apples to a different fruit Replied, post #21 · Compounds › Oral incretins · 28 Nov 2025 · 10 likes Oral versus injectable exposure: comparing a 14 mg oral dose with a 0.5 mg injectable dose is comparing apples to a different fruit. The oral bioavailability is low…
Follow-up: The lowest dose that does anything: is that a real question? Replied, post #76 · Practice › Dosing & titration · 17 Nov 2025 · 3 likes Worth separating two things that post #72 runs together. Reaching a dose and staying there for a year: the question of whether a stable dose remains effective over…
Follow-up: Constipation management, with a dietitian's contribution Replied, post #17 · Practice › Side effects · 4 Nov 2025 · 9 likes Delayed gastric emptying: the mechanism behind much of the gastrointestinal side-effect profile. At extreme magnitudes, severe gastroparesis is a rare but serious…
IGF-1 as a surrogate endpoint and its limitations Replied, post #3 · Compounds › Secretagogues & GH axis · 3 Nov 2025 · 3 likes What a well-designed human trial of a secretagogue would look like: randomised, placebo-controlled, adequate sample size, IGF-1 as primary outcome, muscle and strength…
Payment mechanics and the recovery options that do not exist Replied, post #22 · Sourcing › Payments · 19 Oct 2025 · 0 likes Payment mechanics: most suppliers accept bank transfer, crypto, and some accept credit cards. Each has different risk and different fees. Understand before you commit…
Sleep tracking data and its considerable limitations Replied, post #13 · Wellbeing › Sleep · 16 Oct 2025 · 22 likes Sleep apnoea improvement: as weight is lost, sleep apnoea usually improves. The timeframe is weeks to months, not immediate. Improvement often is gradual rather than…
Pinch or no pinch, and how needle length changes the answer Replied, post #108 · Practice › Administration · 13 Oct 2025 · 10 likes A genuinely late dose: the labelling generally says that if the next dose is more than a couple of days away, take it as soon as you notice. If the next dose is close,…
Compounds this community declines to help with, and why Replied, post #46 · Compounds › Other compounds · 2 Oct 2025 · 0 likes Naming conventions for research peptides cause confusion because suppliers do not follow a standard. The same compound gets different names from different suppliers. If…
About the European Union category Replied, post #6 · Regional › European Union · 25 Sep 2025 · 18 likes On post #2 — agreed on the reasoning, with one qualification. EMA is the regulator with national implementation. Licensed incretin analogues are prescription-only…
The nausea timeline across the first four weeks, with a tabulated log Replied, post #90 · Practice › Side effects · 24 Sep 2025 · 0 likes post #89 is right about the mechanism and I think understates the practical bit. Hair shedding: telogen effluvium associated with rapid weight loss is reported. The…
Coming back to: Where the integrator drew the baseline, and how much it moved the number Replied, post #9 · Analytics › HPLC & UHPLC · 23 Sep 2025 · 22 likes This follows post #6 rather than contradicting it. On integration: where the baseline is drawn matters more than most people realise. On a clean chromatogram with…
Reverse causation in a cohort study of weight and outcome — a second dataset Replied, post #81 · Evidence › Study critique · 15 Sep 2025 · 13 likes Criticise the method, not the author: a paper with a weak design is not a bad paper by someone with bad intentions. It is a paper that answers a limited question.…
Reverse causation in a cohort study of weight and outcome — a second dataset Replied, post #64 · Evidence › Study critique · 14 Sep 2025 · 1 like What makes a methodological criticism substantive: it identifies a specific feature of the design that materially affects what the paper can conclude. "Small sample…
Titles that describe the question, not the situation — what changed since Replied, post #4 · Start Here › How to Ask · 9 Sep 2025 · 33 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Aggregated purity results across four services, with caveats — a second dataset Replied, post #7 · Data & Tools › Datasets · 6 Sep 2025 · 3 likes Combining data from different sources: datasets from this site are not directly comparable to published trials because the populations are different. They are worth…
Column chemistry choices for a 40-residue peptide Replied, post #28 · Analytics › HPLC & UHPLC · 4 Sep 2025 · 7 likes Peak purity: a diode-array detector records a spectrum at every time point. If a peak contains two co-eluting species with different spectra, the spectrum changes…
How the vendor documentation pages are maintained, and by whom — what changed since Replied, post #50 · Sourcing › Vendor reports · 3 Sep 2025 · 23 likes Pattern across lots: a single result is a data point. Three or four results from the same supplier showing a consistent pattern becomes a record worth discussing. Two…
A parcel that arrived warm: a decision process, not a verdict Replied, post #6 · Practice › Storage & stability · 19 Aug 2025 · 5 likes post #5 is right about the mechanism and I think understates the practical bit. Temperature excursions: if a vial sat at room temperature for a time, the question is…
Specification in the result column: why that is a meaningful error Replied, post #30 · Analytics › COA interpretation · 12 Aug 2025 · 5 likes When method identifiers are missing: "reversed-phase HPLC" is less specific than "reversed-phase HPLC at 214 nm on a C18 column with a 10 to 40% acetonitrile gradient…
How to research a compound with no human data without deceiving yourself Replied, post #102 · Compounds › Other compounds · 4 Aug 2025 · 1 like Picking up post #99: that is the part I would want checked first. Distinguishing marketed research compounds from true chemical synthesis: some online suppliers sell…
Coming back to: Amylin analogue mechanism: satiety signalling separate from GLP-1 Replied, post #9 · Compounds › Cagrilintide & amylin analogues · 18 Jul 2025 · 2 likes The CagriSema phase 2 paper: a fixed combination of the two components in one weekly injection. The trade-off of a fixed combination is that you cannot titrate the…
Coming back to: Sample size calculations, read backwards from the published number Replied, post #58 · Evidence › Trials · 18 Jul 2025 · 0 likes This follows post #55 rather than contradicting it. Dropout is information: high dropout rates can indicate tolerability problems or lower efficacy than the summary…
TB-500 and thymosin beta-4: the fragment versus the protein Replied, post #56 · Compounds › Repair & healing peptides · 2 Jul 2025 · 25 likes Reading a preclinical wound-healing model: the model shows whether a mechanism is plausible in a specific context. It does not show magnitude of effect in humans, does…
Journal club: SURMOUNT-1, read without the press release Replied, post #147 · Evidence › Journal club · 28 Jun 2025 · 15 likes Picking up post #144: that is the part I would want checked first. PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not efficacy.…
Follow-up: Tracking intake honestly when appetite is absent Replied, post #27 · Nutrition & Training › Protein & intake · 6 Jun 2025 · 0 likes I read post #25 twice before replying, because I had assumed the opposite. Protein sources: animal sources (meat, fish, eggs, dairy) are denser and easier to hit…
Revisiting: Why a compound being unapproved is not the same as being illegal to possess Replied, post #18 · Sourcing › Regulatory · 4 Jun 2025 · 0 likes Primary documents matter: regulatory positions are published in official documents. Reading the regulatory agency's website directly is more reliable than reading a…
Individual participant data versus aggregate data Replied, post #31 · Evidence › Meta-analyses · 15 May 2025 · 20 likes Number needed to treat from a meta-analysis: can be computed from the pooled estimate if the baseline risk is specified. More interpretable than pooled relative effects.
Why fasting instructions for oral semaglutide are not optional advice — does this still… Replied, post #26 · Compounds › Oral incretins · 2 May 2025 · 0 likes Orforglipron is a small molecule, not a peptide. That changes almost everything: no absorption enhancer required, no fasting window, chemical synthesis instead of…
Splitting a vial for two laboratories: how to do it without ruining both Replied, post #22 · Sourcing › Independent verification · 18 Apr 2025 · 20 likes When results are inconclusive: if a testing service reports "insufficient to verify" on a documentation review, that is not a negative finding about the product. It…
Obstructive sleep apnoea and a hard endpoint in this class Replied, post #51 · Clinical › Comorbidities · 6 Apr 2025 · 0 likes On post #47 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly…
Why cagrilintide alone is discussed so much less than in combination Replied, post #50 · Compounds › Cagrilintide & amylin analogues · 28 Mar 2025 · 32 likes Historical amylin analogues: pramlintide was the only long-acting amylin analogue licensed for some time and its poor adherence was a known limitation. A weekly…
Biased agonism: a real phenomenon, an over-used explanation Replied, post #112 · Pharmacology › Receptor biology · 17 Mar 2025 · 0 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
What a seizure notice actually says Replied, post #41 · Sourcing › Logistics · 11 Mar 2025 · 24 likes Tracking stops updating: tracking last updated days ago usually means the package is in transit and will not update until it reaches the next scanning point. No update…
Certificates issued by the seller versus by a laboratory Replied, post #3 · Analytics › COA interpretation · 11 Mar 2025 · 2 likes When a document puts the specification in the result column, it has told you the release criterion, not the measurement. Those are different claims and the second is…
Follow-up: Requesting a page: what makes a good request Replied, post #7 · Documentation › Wiki requests · 5 Mar 2025 · 4 likes post #6 answers the question as asked. The question underneath it is different. Authority and authorship: if you think a maintained page needs input from someone with…
Pharmaceutical compounding rules, summarised from primary sources Replied, post #125 · Sourcing › Regulatory · 5 Mar 2025 · 23 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
Consistent declarations and why they matter more than clever ones Replied, post #122 · Sourcing › Logistics · 4 Mar 2025 · 0 likes On post #118 — agreed on the reasoning, with one qualification. Customs holds: if a parcel is held at customs and you can contact customs directly, declaring your…
A supplier that answers analytical questions with restated claims Replied, post #16 · Sourcing › Red flags · 28 Jan 2025 · 24 likes post #15 answers the question as asked. The question underneath it is different. Safety documentation absent: a supplier that cannot provide information about sterility…
Distinguishing a deletion sequence by mass alone Replied, post #20 · Analytics › Mass spectrometry · 26 Jan 2025 · 0 likes Worth separating two things that post #16 runs together. Mass accuracy is expressed in parts per million. It is the difference between observed and theoretical mass…
The CagriSema phase 2 paper and what a fixed combination buys Replied, post #2 · Compounds › Cagrilintide & amylin analogues · 13 Jan 2025 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
Follow-up: Tirzepatide's shorter half-life and its one practical consequence Replied, post #133 · Compounds › Tirzepatide · 6 Jan 2025 · 13 likes I read post #131 twice before replying, because I had assumed the opposite. Dual agonism versus dose: how much of tirzepatide's effect is the GIP component and how much…
Revisiting: Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #19 · Compounds › Semaglutide · 19 Dec 2024 · 0 likes The 165 to 184 hour range: that is roughly 7 to 7.6 days, which is why the weekly schedule works. Below 4 half-lives you are not approaching steady state yet, which is…
SURPASS-2 and the comparator dose question that will not go away Replied, post #71 · Compounds › Tirzepatide · 4 Dec 2024 · 23 likes post #70 answers the question as asked. The question underneath it is different. SURMOUNT-1 reported weight reduction of a magnitude that was the largest for a…
Reading a preclinical wound-healing model and its relevance to a human tendon Replied, post #160 · Compounds › Repair & healing peptides · 27 Nov 2024 · 9 likes BPC-157: the preclinical literature is extensive, mostly from a small number of research groups, and reports effects across a wide range of injury models. The breadth…
Second pass at: Food noise reducing and the disorientation that can follow Replied, post #48 · Wellbeing › Mental health · 24 Oct 2024 · 24 likes Disordered eating history: a history of anorexia, bulimia, or other eating disorders changes the risk-benefit calculation. Appetite suppression might trigger relapse.…
Transporting a vial for a weekend away Replied, post #5 · Practice › Storage & stability · 24 Oct 2024 · 1 like Protecting from light: amber vials or opaque containers reduce light exposure. If you are storing for long periods and light matters, this is worth doing. For…
Journal club: STEP 4 and what a withdrawal design can prove — one year on Started this topic · Evidence › Journal club · 13 Oct 2024 · 11 likes Journal club: STEP 4 and what a withdrawal design can prove — one year on Writing it up because I had to work it out twice and would rather nobody else did. Session…
Requesting a page: what makes a good request — what changed since Replied, post #67 · Documentation › Wiki requests · 11 Oct 2024 · 14 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
Second pass at: Hoarding and why it makes a shortage worse Replied, post #18 · Access › Shortages · 9 Oct 2024 · 3 likes Coming back to post #16, because the follow-up matters more than the original answer. Shortage predictions: regulators and suppliers issue shortage alerts before they…
Revisiting: Melanocortin agonists: mechanism and the documented adverse profile Replied, post #29 · Compounds › Other compounds · 3 Oct 2024 · 2 likes Picking up post #26: that is the part I would want checked first. Distinguishing marketed research compounds from true chemical synthesis: some online suppliers sell…
Revisiting: How to bring a laboratory report to an appointment usefully Replied, post #27 · Clinical › Bloodwork · 13 Sep 2024 · 9 likes Reference intervals: constructed to contain the central 95% of a reference population, which means one in twenty healthy people falls outside one by definition. Add…
[2026 update] People with a low starting BMI: where the evidence stops Replied, post #19 · Clinical › Special populations · 6 Sep 2024 · 32 likes post #18 answers the question as asked. The question underneath it is different. Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning…
Correlation in a self-tracked dataset: what it can support Replied, post #84 · Research Methods › Statistics · 23 Aug 2024 · 13 likes Power and sample size: a study might be too small to detect a real effect (low power). Sample size calculations help determine how many participants are needed to…
MHRA statements, read directly — the long version Replied, post #2 · Regional › UK & Ireland · 21 Aug 2024 · 31 likes MHRA is the regulator. Licensed incretin analogues are prescription-only medicines. NHS and private prescribing routes exist with materially different access criteria…
Splitting a vial for two laboratories: how to do it without ruining both — what changed… Replied, post #9 · Sourcing › Independent verification · 21 Aug 2024 · 0 likes How to submit a sample: contact the service directly. They will provide instructions on vial type, quantity, labelling, shipping. Following their instructions exactly…
How this community labels and discusses unrefereed work Replied, post #86 · Evidence › Preprints · 15 Jul 2024 · 8 likes How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.
Assessing a warm arrival: the decision process — one year on Replied, post #70 · Sourcing › Logistics · 31 May 2024 · 23 likes Packaging integrity on arrival: if a parcel arrives with compromised packaging, that is evidence of a handling problem in transit. The contents may or may not be…