Tags · Status
needs a source
A claim in this topic has been challenged and not yet supported.
Related in this group: solved · open question · long read · beginner friendly · worked example · data table · disputed
90 topics · page 2 of 3
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Follow-up: Evidence quality in the secretagogue literature: an honest assessment
On the subject in the title: Evidence quality in the secretagogue literature: an honest assessment Working notes rather than a conclusion. Comparing PIONEER 6 ( N Engl J Med , 2019) with LEADER ( N Engl J Med…
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+20 | 24 | 18k | 4mo |
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Grapefruit: why this class is not the class that cares
Grapefruit: why this class is not the class that cares Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…
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+126 | 139 | 4k | 4mo |
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Preprint servers and what screening they do — the long version
On the subject in the title: Preprint servers and what screening they do — the long version Working notes rather than a conclusion. Session topic: PIONEER 6 ( N Engl J Med , 2019). Please read it before…
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+7 | 11 | 26k | 4mo |
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Preprint servers and what screening they do
Preprint servers and what screening they do — setting out what I have, and where I think it stops being reliable. I have seen FLOW ( N Engl J Med , 2024) cited in support of a claim I do not think it…
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+95 | 106 | 5.6k | 4mo |
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Follow-up: Levothyroxine timing: a real interaction with a simple fix
On the subject in the title: Levothyroxine timing: a real interaction with a simple fix Working notes rather than a conclusion. Reporting something rather than asking about it, in case the pattern is useful…
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+2 | 6 | 8.1k | 4mo |
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IGF-1 as a surrogate endpoint and its limitations
IGF-1 as a surrogate endpoint and its limitations Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURPASS-4 ( Lancet , 2021) cited in support of a claim I do not…
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+5 | 9 | 35k | 4mo |
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Reading an interaction checker output critically
On the subject in the title: Reading an interaction checker output critically Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking rather than…
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+144 | 152 | 3k | 4mo |
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Warfarin and altered intake: the monitoring argument
Warfarin and altered intake: the monitoring argument — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still have a gap, so I am asking rather…
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2 | 11k | 4mo | |
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Warfarin and altered intake: the monitoring argument — the long version
Posting this under the heading it deserves: Warfarin and altered intake: the monitoring argument — the long version Everything below is what sits behind that. Reporting something rather than asking about it,…
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+123 | 134 | 40k | 4mo |
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Oral versus injected administration claims for BPC-157
Oral versus injected administration claims for BPC-157 — setting out what I have, and where I think it stops being reliable. I have seen FLOW ( N Engl J Med , 2024) cited in support of a claim I do not think…
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+20 | 24 | 47k | 4mo |
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Citing a preprint in a maintained document: our rule and its reasoning
On the subject in the title: Citing a preprint in a maintained document: our rule and its reasoning Working notes rather than a conclusion. I have seen SELECT ( N Engl J Med , 2023) cited in support of a…
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2 | 467 | 4mo | |
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Coming back to: Reading a supplier's product description as a marketing document
Reading a supplier's product description as a marketing document Writing it up because I had to work it out twice and would rather nobody else did. I have seen SUSTAIN 6 ( N Engl J Med , 2016) cited in…
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+35 | 39 | 688 | 5mo |
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Alcohol: what is documented and what is folklore — the long version
Alcohol: what is documented and what is folklore — the long version — setting out what I have, and where I think it stops being reliable. Reporting something rather than asking about it, in case the pattern…
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+9 | 13 | 7.3k | 6mo |
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AOD-9604 and the fragment hypothesis, revisited
Posting this under the heading it deserves: AOD-9604 and the fragment hypothesis, revisited Everything below is what sits behind that. Comparing SURPASS-2 ( N Engl J Med , 2021) with SUSTAIN 6 ( N Engl J Med…
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+40 | 44 | 2.8k | 6mo |
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About the Other compounds category
Anything not covered by a dedicated subcategory, including research-use-only material with no human data. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…
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+8 | 12 | 51k | 7mo |
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[2026 update] Conference abstracts as evidence: the weakest common citation
Conference abstracts as evidence: the weakest common citation — setting out what I have, and where I think it stops being reliable. Comparing STEP 4 ( JAMA , 2021) with SURMOUNT-4 ( JAMA , 2024) and finding…
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2 | 48k | 7mo | |
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Tracking a preprint to publication: a worked example
Tracking a preprint to publication: a worked example Writing it up because I had to work it out twice and would rather nobody else did. Session topic: STEP 1 ( N Engl J Med , 2021). Please read it before…
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+133 | 147 | 15k | 7mo |
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A preprint whose numbers changed substantially at publication — what changed since
On the subject in the title: A preprint whose numbers changed substantially at publication — what changed since Working notes rather than a conclusion. Session topic: STEP 2 ( Lancet , 2021). Please read it…
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+3 | 7 | 125 | 8mo |
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Sequence verification for an obscure compound: how it is done — what changed since
On the subject in the title: Sequence verification for an obscure compound: how it is done — what changed since Working notes rather than a conclusion. Session topic: PIONEER 6 ( N Engl J Med , 2019). Please…
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+100 | 108 | 1.3k | 8mo |
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Reading a supplier's product description as a marketing document
On the subject in the title: Reading a supplier's product description as a marketing document Working notes rather than a conclusion. I have seen PIONEER 6 ( N Engl J Med , 2019) cited in support of a claim I…
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+86 | 97 | 62k | 8mo |
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Conference abstracts as evidence: the weakest common citation
On the subject in the title: Conference abstracts as evidence: the weakest common citation Working notes rather than a conclusion. Session topic: SURMOUNT-1 ( N Engl J Med , 2022). Please read it before…
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+1 | 5 | 2k | 9mo |
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Research-use-only status: what it means legally and practically — does this still hold?
Asking directly, because I could not find a straight answer: Research-use-only status: what it means legally and practically — does this still hold? Session topic: SELECT ( N Engl J Med , 2023). Please read…
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2 | 309 | 9mo | |
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A preprint whose numbers changed substantially at publication
A preprint whose numbers changed substantially at publication — setting out what I have, and where I think it stops being reliable. Session topic: SURMOUNT-2 ( Lancet , 2023). Please read it before posting;…
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+90 | 95 | 21k | 9mo |
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Compounds this community declines to help with, and why
Compounds this community declines to help with, and why — setting out what I have, and where I think it stops being reliable. Comparing LEADER ( N Engl J Med , 2016) with SCALE ( N Engl J Med , 2015) and…
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+81 | 87 | 35k | 10mo |
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Why catalogue breadth is not evidence of anything — what changed since
Asking directly, because I could not find a straight answer: Why catalogue breadth is not evidence of anything — what changed since Session topic: SURMOUNT-1 ( N Engl J Med , 2022). Please read it before…
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+62 | 66 | 26k | 10mo |
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Citing a preprint in a maintained document: our rule and its reasoning — does this still hold?
The question in the title: Citing a preprint in a maintained document: our rule and its reasoning — does this still hold? I will give what I have already checked below so nobody repeats it. I have seen LEADER…
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+103 | 115 | 24k | 10mo |
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Reading a rodent study on a secretagogue without over-extrapolating
Posting this under the heading it deserves: Reading a rodent study on a secretagogue without over-extrapolating Everything below is what sits behind that. I have seen STEP 8 ( JAMA , 2022) cited in support of…
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+50 | 54 | 32k | 10mo |
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BPC-157: what the rodent literature actually shows, and what it does not
BPC-157: what the rodent literature actually shows, and what it does not — setting out what I have, and where I think it stops being reliable. I have seen LEADER ( N Engl J Med , 2016) cited in support of a…
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+44 | 48 | 3k | 10mo |
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Analytical identity of BPC-157: a 15-mer with a simple mass
Analytical identity of BPC-157: a 15-mer with a simple mass Writing it up because I had to work it out twice and would rather nobody else did. Comparing SURMOUNT-OSA ( N Engl J Med , 2024) with STEP 2 (…
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+3 | 7 | 5.2k | 10mo |
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Second pass at: Why this subcategory is stricter about sourcing than most
Second pass at: Why this subcategory is stricter about sourcing than most — setting out what I have, and where I think it stops being reliable. Comparing LEADER ( N Engl J Med , 2016) with SURMOUNT-4 ( JAMA ,…
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+120 | 129 | 61k | 11mo |