d.ferreira

TL2 Moderator · Bochum

Contributes reviews on supplier material. Based in Bochum.

Joined 17 June 2025 · last posted 1d

93 posts, newest first. Showing up to 150.

[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #74 · Analytics › HPLC & UHPLC · 27 Jul 2026 · 3 likes Method validation is the demonstration that a method can separate the compound from its degradation products and impurities reliably. A method that cannot resolve an…
What to bring: records that a clinician can actually use — a second dataset Replied, post #82 · Clinical › Prescriber conversations · 27 Jul 2026 · 1 like Questions about dose: asking "how will we determine whether this dose is working for me" gets at the monitoring plan. Asking "can we start lower" or "can we escalate…
GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Replied, post #53 · Compounds › Secretagogues & GH axis · 26 Jul 2026 · 12 likes I read post #51 twice before replying, because I had assumed the opposite. Evidence quality in the secretagogue literature is honestly weaker than in the incretin…
Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #66 · Compounds › Retatrutide · 16 Jul 2026 · 12 likes How to read phase 2 without treating it as phase 3: phase 2 establishes that a dose range produces an effect and is tolerable enough to justify large trials. It does…
Immortal time bias in a claims-database study — one year on Replied, post #24 · Evidence › Study critique · 15 Jul 2026 · 11 likes Worth separating two things that post #20 runs together. Building consensus on which criticisms matter: if everyone agrees that the sample size is small but only you…
Submitting a sample: the process end to end Replied, post #76 · Sourcing › Independent verification · 12 Jul 2026 · 2 likes Blind sampling: submitting without the laboratory or seller knowing the source removes the two easiest ways for a result to be shaped: selective submission and…
Heart failure with preserved ejection fraction: symptom endpoints Replied, post #18 · Clinical › Comorbidities · 8 Jul 2026 · 0 likes Bariatric surgery history: altered anatomy after surgery affects absorption. That matters for oral medications and for reconstituted solutions. Discussing specific…
How shortages have affected compounding permissions Replied, post #19 · Access › Shortages · 6 Jul 2026 · 32 likes Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.
HbA1c lag and what it can and cannot tell you at eight weeks — one year on Replied, post #16 · Clinical › Bloodwork · 4 Jul 2026 · 0 likes A single value outside interval: usually uninformative on a single draw. What makes a result interesting: a trend across multiple draws, a magnitude well beyond the…
Personal or family history of medullary thyroid carcinoma Replied, post #32 · Safety › Contraindications · 30 Jun 2026 · 0 likes Concurrent insulin or sulfonylureas: not an absolute contraindication but requires dose adjustment and close monitoring for hypoglycemia. The combination is used with…
[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #40 · Access › International · 27 Jun 2026 · 2 likes I read post #38 twice before replying, because I had assumed the opposite. Customs and import outcomes: different routes have different seizure rates. Some countries…
A reconstituted vial's beyond-use date and the reasoning behind common figures Replied, post #127 · Practice › Storage & stability · 10 Jun 2026 · 1 like Protecting from light: amber vials or opaque containers reduce light exposure. If you are storing for long periods and light matters, this is worth doing. For…
Reading a trial's population section before its results Replied, post #90 · Evidence › Trials · 5 Jun 2026 · 0 likes Coming back to post #88, because the follow-up matters more than the original answer. Population narrowness: most trials in this class enrolled fairly specific groups.…
[2026 update] A vial that will not fully dissolve: what to check and in what order Replied, post #83 · Practice › Reconstitution · 1 Jun 2026 · 2 likes This follows post #80 rather than contradicting it. I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The…
Does dual agonism explain the effect size, or is it dose? Replied, post #7 · Compounds › Tirzepatide · 29 May 2026 · 0 likes I read post #5 twice before replying, because I had assumed the opposite. Mass and charge states: tirzepatide is about 4813.5 Da and on an electrospray instrument you…
The anatomy of a question that gets answered within an hour Replied, post #58 · Start Here › How to Ask · 27 May 2026 · 0 likes Context that matters: compound, how long in, current dose, relevant history. Context that does not matter: how you feel, your hopes for the outcome, your medical…
[2026 update] A vial that will not fully dissolve: what to check and in what order Replied, post #68 · Practice › Reconstitution · 23 May 2026 · 27 likes On post #64 — agreed on the reasoning, with one qualification. A vial that will not fully dissolve: check in order: is the diluent genuinely room temperature (some…
A checklist for reading a certificate in under two minutes Replied, post #21 · Analytics › COA interpretation · 15 May 2026 · 16 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
About the Insurance & coverage category Replied, post #5 · Access › Insurance & coverage · 30 Apr 2026 · 13 likes Prior authorisation: pre-approval requirements and how to satisfy them. Most denials cite specific criteria. Understanding the criterion is the first step in satisfying…
Comparing documentation quality across the directory, tabulated Started this topic · Sourcing › Vendor reports · 29 Apr 2026 · 1 like Comparing documentation quality across the directory, tabulated — setting out what I have, and where I think it stops being reliable. I would like to talk about…
How Janoshik, Medutest, PeptideMeter and VendorInvestigate differ — a second dataset Replied, post #42 · Sourcing › Independent verification · 28 Apr 2026 · 30 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Coming back to: Reconciling a supplier certificate with an independent result Started this topic · Sourcing › Vendor reports · 28 Apr 2026 · 10 likes Posting this under the heading it deserves: Reconciling a supplier certificate with an independent result Everything below is what sits behind that. Structured report…
[2026 update] 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #60 · Devices › Syringes & needles · 25 Apr 2026 · 14 likes post #59 is right about the mechanism and I think understates the practical bit. For anyone arriving from a search: the marked solution above is the direct answer, and…
[2026 update] Charge states for a 4 kDa peptide, worked through Replied, post #79 · Analytics › Mass spectrometry · 13 Apr 2026 · 0 likes Desalting before analysis: some samples need desalting to remove salts that suppress the peptide signal. Report whether desalting was used, because it can affect the…
Pregnancy and pregnancy planning: contraindication and washout Replied, post #108 · Clinical › Special populations · 13 Apr 2026 · 25 likes Picking up post #105: that is the part I would want checked first. Renal impairment: the compounds are cleared renally to some degree. Dose adjustments might be needed…
The "under review" status pill and when a moderator applies it Replied, post #42 · Evidence › Preprints · 28 Mar 2026 · 0 likes On post #38 — agreed on the reasoning, with one qualification. Two things before anyone answers the substance. First, the context in the first post is clear and…
The lowest dose that does anything: is that a real question? Replied, post #108 · Practice › Dosing & titration · 8 Mar 2026 · 18 likes post #107 is right about the mechanism and I think understates the practical bit. Titrating on tolerability rather than on the calendar: some people escalate when they…
[2026 update] What a purity-only report leaves out Replied, post #39 · Sourcing › Independent verification · 1 Mar 2026 · 0 likes Cost and turnaround: different services have different pricing and turnaround times. Janoshik's turnaround is weeks by mail; VendorInvestigate documentation review is…
Why one laboratory's 98.4% and another's 96.1% may not contradict — one year on Replied, post #10 · Analytics › Method validation · 21 Feb 2026 · 0 likes I read post #8 twice before replying, because I had assumed the opposite. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so…
Why "dose equivalence" between different incretin analogues is a weak concept Replied, post #35 · Practice › Dosing & titration · 16 Feb 2026 · 25 likes This follows post #32 rather than contradicting it. Steady state means the plasma concentration is stable from dose to dose. That happens around 4 to 5 half-lives.…
Revisiting: Language barriers in accessing a prescription abroad Replied, post #109 · Access › International · 14 Feb 2026 · 24 likes On post #105 — agreed on the reasoning, with one qualification. Country-by-country legality: compound approval and legal status differ substantially by jurisdiction.…
Why semaglutide solutions can look faintly opalescent and when that matters Replied, post #64 · Compounds › Semaglutide · 6 Feb 2026 · 0 likes Is there a ceiling dose beyond which the effect plateaus? The trials did not study that because they stopped at 2.4 mg. Some people report trying higher doses, but…
MHRA statements, read directly Replied, post #67 · Regional › UK & Ireland · 13 Jan 2026 · 1 like Private prescribing is legal and widespread, including through remote consultation. Pharmacies must satisfy themselves that a prescription is clinically appropriate.…
Personal import allowances, compared — a second dataset Replied, post #47 · Access › International · 5 Jan 2026 · 27 likes Licensed prescribing: where a compound is approved, prescribing is restricted to licensed prescribers. Where it is not approved, the legality of possession and use is…
[2026 update] What a good consultation looks like from the other side Replied, post #10 · Clinical › Prescriber conversations · 4 Jan 2026 · 27 likes Picking up post #7: that is the part I would want checked first. What to bring: copies of relevant lab results, pharmacy records (to confirm doses actually taken), and…
Which panel is worth repeating and which is worth ignoring — a second dataset Replied, post #38 · Clinical › Bloodwork · 27 Dec 2025 · 12 likes post #37 is right about the mechanism and I think understates the practical bit. Renal function markers: eGFR is estimated, not measured. It depends on creatinine, age,…
Request declined, with reasoning — what changed since Replied, post #2 · Meta › Feature requests · 25 Dec 2025 · 12 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Half-life, steady state, and accumulation worked through — a second dataset Replied, post #42 · Pharmacology › Pharmacokinetics · 21 Dec 2025 · 5 likes Hepatic metabolism: the degree to which each compound is hepatically metabolised versus renally cleared is known but varies. Severe liver disease changes clearance.
Heterogeneity as information rather than as a nuisance Replied, post #27 · Evidence › Meta-analyses · 16 Dec 2025 · 9 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
Reused chromatograms across lots: how to spot it Replied, post #8 · Analytics › COA interpretation · 14 Dec 2025 · 0 likes Worth separating two things that post #4 runs together. Amino acid analysis gives content: it hydrolyses the peptide and quantifies the residues. It measures the…
What pooling buys you and what it destroys Replied, post #76 · Evidence › Meta-analyses · 26 Nov 2025 · 7 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Pharmaceutical compounding rules, summarised from primary sources — a second dataset Replied, post #26 · Sourcing › Regulatory · 12 Nov 2025 · 15 likes Off-label use and medical practice: clinicians can prescribe approved medications off-label under some circumstances. That is different from research-use-only…
The anatomy of a question that gets answered within an hour — the long version Replied, post #53 · Start Here › How to Ask · 3 Nov 2025 · 14 likes The specific question in the title is more useful than you might think. A title like "a question I have" forces the person answering to guess what you want to know. A…
Sleep quality changes during weight loss — what changed since Replied, post #34 · Wellbeing › Sleep · 21 Oct 2025 · 3 likes Gastrointestinal effects overnight: nausea or reflux or constipation at night can disrupt sleep. Dosing timing (morning versus evening) might help if nighttime GI…
Older adults, sarcopenia risk, and the trade-off nobody quantifies Replied, post #10 · Clinical › Special populations · 8 Oct 2025 · 1 like Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning windows (how long to wait before attempting pregnancy) are not formally…
What pooling buys you and what it destroys Replied, post #36 · Evidence › Meta-analyses · 6 Oct 2025 · 8 likes Funnel plots: a plot of study effect size versus sample size that helps detect publication bias. If small studies are missing on the negative side, the funnel is…
What a purity-only report leaves out Replied, post #31 · Sourcing › Independent verification · 1 Oct 2025 · 0 likes On post #27 — agreed on the reasoning, with one qualification. Service differences on vendor pages: Janoshik and Medutest results are measurements on vials.…
The most useful thing you learned here that was not the answer you came for — a second… Replied, post #50 · Lounge › Off topic · 22 Sep 2025 · 0 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Substitution between formats during a shortage Replied, post #59 · Access › Shortages · 18 Sep 2025 · 15 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Revisiting: Reading a denial letter as a specification for your appeal Replied, post #117 · Access › Insurance & coverage · 12 Sep 2025 · 0 likes Reimbursement changes: a compound covered one year might not be the next. A formulary decision in January can change by April. Checking again before refilling saves…
Aggregated purity results across four services, with caveats — a second dataset Replied, post #123 · Data & Tools › Datasets · 11 Sep 2025 · 6 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
A ten-fold dose error caught before injection Replied, post #95 · Devices › Syringes & needles · 6 Sep 2025 · 14 likes Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and…
Follow-up: Journal club: orforglipron phase 2 and the non-peptide question Replied, post #52 · Evidence › Journal club · 27 Aug 2025 · 9 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
[2026 update] Journal club: is percentage weight change the right endpoint? Replied, post #14 · Evidence › Journal club · 11 Aug 2025 · 15 likes SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral formulation. Note that oral bioavailability is lower…
A request that was declined, and the reasoning — a second dataset Replied, post #9 · Documentation › Wiki requests · 5 Aug 2025 · 8 likes Worth separating two things that post #5 runs together. Accessibility feedback: if you have trouble accessing or reading a maintained page (screen reader issues,…
Why catalogue breadth is not evidence of anything — what changed since Replied, post #12 · Compounds › Other compounds · 4 Aug 2025 · 0 likes post #11 answers the question as asked. The question underneath it is different. Reading a supplier's product description as a marketing document: that is exactly what…
Domestic fridge temperature mapping: a cheap experiment — what changed since Replied, post #156 · Devices › Cold chain · 4 Aug 2025 · 7 likes Reconstituted solutions: once reconstituted, solutions are less stable than lyophilised powder. Refrigerate prepared solutions immediately after preparation. Most…
How to research a compound with no human data without deceiving yourself Replied, post #90 · Compounds › Other compounds · 3 Aug 2025 · 0 likes Coming back to post #88, because the follow-up matters more than the original answer. Practical note that does not fit anywhere else. Whatever you conclude from this…
When a preprint is the best available evidence and we say so Replied, post #17 · Evidence › Preprints · 2 Aug 2025 · 0 likes On post #13 — agreed on the reasoning, with one qualification. How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted…
"Greater than or equal to 99%" as a specification rather than a result Replied, post #10 · Analytics › COA interpretation · 22 Jul 2025 · 32 likes Endotoxin testing is separate: a certificate of purity says nothing about endotoxin. A chemically pure preparation can carry a clinically significant endotoxin load. If…
Meeting a protein target on a suppressed appetite Replied, post #9 · Nutrition & Training › Protein & intake · 11 Jul 2025 · 4 likes Leucine and MPS: leucine stimulates muscle protein synthesis at a threshold of roughly 2 to 3 grams per meal. That influences how much protein per meal matters, but…
Coming back to: Oxidation and deamidation mass shifts, tabulated Replied, post #17 · Analytics › Mass spectrometry · 29 Jun 2025 · 0 likes Charge states observed: for semaglutide (4113.6 Da) the doubly charged ion appears at m/z ≈ 2057, triply charged at ≈ 1371, quadruply at ≈ 1029. Those are the positions…
Repeatability versus intermediate precision Replied, post #78 · Analytics › Method validation · 27 Jun 2025 · 28 likes Accuracy: the method measures what you intend to measure. For purity methods, this is tested by spike-and-recover experiments: add a known amount of impurity to a…
The CagriSema phase 2 paper and what a fixed combination buys Replied, post #56 · Compounds › Cagrilintide & amylin analogues · 16 Jun 2025 · 0 likes Gastric emptying: both amylin and GLP-1 slow it, through partly overlapping but distinct mechanisms. Whether the slowing at a higher magnitude produces disproportionate…
Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly Replied, post #108 · Compounds › Tirzepatide · 12 Jun 2025 · 0 likes SURMOUNT-4 used a randomised withdrawal design: everyone titrated, then those on maintenance were randomised to continue or placebo. Continuation maintained effect;…
Journal club: SURMOUNT-4 and continuation versus withdrawal — a second dataset Replied, post #48 · Evidence › Journal club · 10 Jun 2025 · 14 likes I read post #46 twice before replying, because I had assumed the opposite. Critical appraisal template: (1) What did the trial set out to estimate? (2) Could the design…
Reconstituting a multi-strength kit without mixing yourself up Replied, post #82 · Practice › Reconstitution · 7 Jun 2025 · 10 likes Osmolarity and reconstitution: the osmolarity of the reconstituted solution affects comfort on injection. Isotonic solutions (close to blood osmolarity) are less…
Anxiety in the first weeks: drug, situation, or both Replied, post #97 · Wellbeing › Mental health · 3 Jun 2025 · 1 like Coming back to post #95, because the follow-up matters more than the original answer. Practical note that does not fit anywhere else. Whatever you conclude from this…
A claim built entirely on a subgroup analysis Replied, post #66 · Evidence › Study critique · 31 May 2025 · 4 likes What makes a methodological criticism substantive: it identifies a specific feature of the design that materially affects what the paper can conclude. "Small sample…
Revisiting: German, French and Dutch differences, compared Replied, post #26 · Regional › European Union · 27 May 2025 · 0 likes Cross-border purchase rules: buying a prescription in one EU country and bringing it home is complex. The substance is legal but crossing borders with it requires…
Request: a diff view for wiki revisions — the long version Replied, post #4 · Meta › Feature requests · 26 May 2025 · 1 like Feature scope: some requests are for the site itself (search, filtering, navigation). Some are for the documentation (new topics, different formats). Scope helps…
Reading a regulatory notice rather than an article about it — what changed since Replied, post #7 · Sourcing › Regulatory · 24 May 2025 · 3 likes Research-use-only status is a legal classification, not a safety classification. It means the compound is sold for laboratory use and not for human consumption. The…
Half-life, steady state, and accumulation worked through Replied, post #10 · Pharmacology › Pharmacokinetics · 22 May 2025 · 0 likes post #9 is right about the mechanism and I think understates the practical bit. Fasting requirement for oral semaglutide: food and large fluid volumes reduce…
Pregnancy as an absolute contraindication Replied, post #63 · Safety › Contraindications · 19 May 2025 · 8 likes Concurrent insulin or sulfonylureas: not an absolute contraindication but requires dose adjustment and close monitoring for hypoglycemia. The combination is used with…
Second pass at: Designing a personal experiment that could change your mind Replied, post #11 · Research Methods › N-of-1 designs · 17 May 2025 · 2 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
A report I filed that turned out to be wrong, and the correction Replied, post #43 · Sourcing › Vendor reports · 7 May 2025 · 1 like Worth separating two things that post #39 runs together. Testing service selection: Janoshik gives purity with chromatogram. Medutest gives combined purity and…
When to stop reading forums, including this one — the long version Replied, post #4 · Wellbeing › Mental health · 28 Apr 2025 · 25 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Micronutrient status when intake falls substantially — a second dataset Replied, post #13 · Clinical › Bloodwork · 28 Apr 2025 · 17 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
Follow-up: Journal club: the retatrutide phase 2 obesity paper Replied, post #23 · Evidence › Journal club · 8 Apr 2025 · 3 likes SELECT (N Engl J Med 2023): Semaglutide cardiovascular outcomes without diabetes. The first outcome trial in people without diabetes, which decoupled the cardiovascular…
What happens after your first post: likes, trust levels, and why none of it matters much Replied, post #11 · Start Here › Welcome · 26 Mar 2025 · 0 likes Worth separating two things that post #7 runs together. There is no stupid-questions rule and no penalty for asking badly. The response to a poorly framed question is a…
How compounding permissions changed when supply normalised Replied, post #26 · Sourcing › Regulatory · 4 Mar 2025 · 5 likes Off-label use and medical practice: clinicians can prescribe approved medications off-label under some circumstances. That is different from research-use-only…
Validating a method you did not develop — does this still hold? Replied, post #69 · Analytics › Method validation · 4 Mar 2025 · 0 likes On post #65 — agreed on the reasoning, with one qualification. System suitability: injections run at the start of a batch to establish that the instrument and column…
What the published dose-response for semaglutide actually looks like above 2.4 mg — a… Replied, post #86 · Compounds › Semaglutide · 3 Mar 2025 · 5 likes I read post #84 twice before replying, because I had assumed the opposite. The mass figure differs between sources because of how the different entities report it. The…
Reading an MS report that only gives you a single number Replied, post #19 · Analytics › Mass spectrometry · 28 Feb 2025 · 19 likes Sample matrix effects: if a sample is dissolved in a complex matrix, other compounds in the matrix can suppress the peptide signal. Clean samples give higher…
Amylin analogue mechanism: satiety signalling separate from GLP-1 Replied, post #66 · Compounds › Cagrilintide & amylin analogues · 15 Feb 2025 · 6 likes Historical amylin analogues: pramlintide was the only long-acting amylin analogue licensed for some time and its poor adherence was a known limitation. A weekly…
Oral semaglutide bioavailability and its variability between people — a second dataset Replied, post #78 · Compounds › Oral incretins · 27 Dec 2024 · 0 likes Coming back to post #76, because the follow-up matters more than the original answer. PIONEER programme is phase 3 for oral semaglutide. The trials cover multiple…
Molecular mass of semaglutide and why the figure differs between sources — does this… Replied, post #35 · Compounds › Semaglutide · 20 Dec 2024 · 0 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
Reading a supplementary appendix and finding the interesting part Replied, post #44 · Evidence › Trials · 15 Dec 2024 · 0 likes This follows post #41 rather than contradicting it. Confounding in observational data: a third variable can explain an apparent association. In a randomised trial,…
A revision dispute resolved on the topic rather than in the history — a second dataset Replied, post #45 · Meta › Wiki maintenance · 23 Nov 2024 · 0 likes This follows post #42 rather than contradicting it. For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add…
Why we hide unevidenced fraud accusations and log the hiding Replied, post #14 · Sourcing › Red flags · 10 Nov 2024 · 11 likes Safety documentation absent: a supplier that cannot provide information about sterility testing, endotoxin testing, or safety documentation when asked is raising flags.
Coming back to: Research-use-only labelling: what it means and what it does not Replied, post #23 · Sourcing › Regulatory · 7 Nov 2024 · 3 likes Labelling and intended use: a compound sold as "research-use-only" does not change its pharmacology if ingested. It changes the legal status of the sale. The labelling…
Splitting a vial for two laboratories: how to do it without ruining both — what changed… Replied, post #73 · Sourcing › Independent verification · 20 Sep 2024 · 12 likes Service differences on vendor pages: Janoshik and Medutest results are measurements on vials. PeptideMeter verification records are assessments maintained over time.…
The C-cell question: rodent findings and their human context — what changed since Replied, post #34 · Compounds › Semaglutide · 3 Sep 2024 · 17 likes I read post #32 twice before replying, because I had assumed the opposite. Semaglutide versus liraglutide in STEP 8: semaglutide produced greater weight reduction and…