Latest topics page 11
Topics ordered by most recent activity across all 71 subcategories.
1,535 topics · page 11 of 52
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Gradient steepness and apparent purity: a worked comparison — the long version
Gradient steepness and apparent purity: a worked comparison — the long version — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I…
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2 | 32k | 1d | |
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[2026 update] Temperature indicator cards: worth asking for?
Temperature indicator cards: worth asking for? I have a specific reason for asking rather than idle curiosity, and the context is below. A logistics question, since the answers here are usually better than…
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+21 | 26 | 4.5k | 1d |
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Cleaning a self-reported dataset and what you throw away
Cleaning a self-reported dataset and what you throw away — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a certificate in…
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2 | 28k | 1d | |
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Washout with a one-week half-life: the arithmetic — does this still hold?
Washout with a one-week half-life: the arithmetic — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing SURPASS-2 ( N Engl J Med , 2021)…
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+41 | 45 | 12k | 1d |
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[2026 update] Documenting an adverse event properly
Documenting an adverse event properly Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The published trials in this…
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+18 | 22 | 4.3k | 1d |
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Why the Start Here categories exist, and what they are not for
Why the Start Here categories exist, and what they are not for — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title. Context below, and I have tried…
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+40 | 44 | 32k | 1d |
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile
Posting this under the heading it deserves: Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Everything below is what sits behind that. I have seen SCALE ( N Engl J Med…
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+115 | 122 | 2.6k | 1d |
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Sulphur-smelling eructation: mechanism and what helps
Sulphur-smelling eructation: mechanism and what helps — setting out what I have, and where I think it stops being reliable. Reporting something rather than asking about it, in case the pattern is useful to…
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2 | 58 | 1d | |
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset
Posting this under the heading it deserves: Muscle cramps: the ordinary causes before the exotic ones — a second dataset Everything below is what sits behind that. Reporting something rather than asking about…
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+65 | 77 | 39k | 1d |
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Publication bias detection and its low power
On the subject in the title: Publication bias detection and its low power Working notes rather than a conclusion. I have seen SURMOUNT-1 ( N Engl J Med , 2022) cited in support of a claim I do not think it…
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2 | 3.2k | 1d | |
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Conditions that change the calculus rather than forbidding it
Conditions that change the calculus rather than forbidding it Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The…
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+28 | 32 | 6.1k | 1d |
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Type 1 diabetes: off-label use and the evidence gap
On the subject in the title: Type 1 diabetes: off-label use and the evidence gap Working notes rather than a conclusion. General question, not a request for advice about my own care — I know the difference…
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2 | 2.3k | 1d | |
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Splitting an overlong document into two
Posting this under the heading it deserves: Splitting an overlong document into two Everything below is what sits behind that. Nominating something for promotion into the documentation commons. The topic in…
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+30 | 34 | 6.2k | 1d |
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What is genuinely unknown about long-term amylin agonism
What is genuinely unknown about long-term amylin agonism — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing STEP 8 ( JAMA , 2022) with SURMOUNT-1 ( N Engl J Med…
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+83 | 91 | 46k | 1d |
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Why the absence of controlled human data on BPC-157 matters more than people admit
Why the absence of controlled human data on BPC-157 matters more than people admit — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing STEP 8 ( JAMA , 2022) with…
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+60 | 66 | 16k | 1d |
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Pinch or no pinch, and how needle length changes the answer — what changed since
Posting this under the heading it deserves: Pinch or no pinch, and how needle length changes the answer — what changed since Everything below is what sits behind that. I have read the maintained page on this…
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+58 | 62 | 16k | 1d |
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System suitability injections: if they failed, the run did not happen — the long version
System suitability injections: if they failed, the run did not happen — the long version — setting out what I have, and where I think it stops being reliable. A documentation question rather than an…
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+2 | 6 | 6.2k | 1d |
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Revisiting: How this community labels and discusses unrefereed work
Revisiting: How this community labels and discusses unrefereed work Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURMOUNT-OSA ( N Engl J Med , 2024) cited in…
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+31 | 35 | 7k | 1d |
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Peak-to-trough ratio at steady state for a weekly agent — the long version
Peak-to-trough ratio at steady state for a weekly agent — the long version Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means…
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+57 | 61 | 708 | 1d |
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What published stability data actually covers, and what it does not
Asking directly, because I could not find a straight answer: What published stability data actually covers, and what it does not Reporting something rather than asking about it, in case the pattern is useful…
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+8 | 12 | 435 | 1d |
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Journal club: SUSTAIN 6 and its retinopathy signal
On the subject in the title: Journal club: SUSTAIN 6 and its retinopathy signal Working notes rather than a conclusion. I have seen SELECT ( N Engl J Med , 2023) cited in support of a claim I do not think it…
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+110 | 122 | 46k | 1d |
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Revisiting: The report format the maintainers ask for, and why each field is there
Posting this under the heading it deserves: Revisiting: The report format the maintainers ask for, and why each field is there Everything below is what sits behind that. Structured report rather than an…
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+100 | 108 | 57k | 1d |
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Distinguishing a red flag from an inconvenience — a second dataset
On the subject in the title: Distinguishing a red flag from an inconvenience — a second dataset Working notes rather than a conclusion. A logistics question, since the answers here are usually better than…
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+8 | 12 | 9.6k | 1d |
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Athletes in weight-category sports: a different risk calculus
Athletes in weight-category sports: a different risk calculus — setting out what I have, and where I think it stops being reliable. General question, not a request for advice about my own care — I know the…
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+38 | 42 | 6.6k | 1d |
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The five documentation pages worth reading before you post anything — a second dataset
On the subject in the title: The five documentation pages worth reading before you post anything — a second dataset Working notes rather than a conclusion. Question in the title. Context below, and I have…
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2 | 24k | 1d | |
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Research-use-only status: what it means legally and practically
Research-use-only status: what it means legally and practically Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURMOUNT-OSA ( N Engl J Med , 2024) cited in…
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+72 | 81 | 44k | 1d |
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Does a peptide degrade silently, with no visual change?
Does a peptide degrade silently, with no visual change? I have a specific reason for asking rather than idle curiosity, and the context is below. I have read the maintained page on this and I still have a…
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+73 | 79 | 1.3k | 1d |
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PCOS and metabolic overlap: what is and is not studied
On the subject in the title: PCOS and metabolic overlap: what is and is not studied Working notes rather than a conclusion. Asking about a population rather than about a person. The published trials in this…
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3 | 6.6k | 1d | |
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An appeal that succeeded, with the letter structure
On the subject in the title: An appeal that succeeded, with the letter structure Working notes rather than a conclusion. Documenting an access outcome, dated, because everything in this category expires. As…
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+12 | 16 | 15k | 1d |
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The most useful thing you learned here that was not the answer you came for
The most useful thing you learned here that was not the answer you came for Writing it up because I had to work it out twice and would rather nobody else did. Lower-stakes topic, but the sourcing rule still…
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+54 | 61 | 57k | 1d |