Latest topics page 4

Topics ordered by most recent activity across all 71 subcategories.

1,535 topics · page 4 of 52

Topic	Participants	Replies	Views	Activity
About the Vendor reports category Sourcing › Vendor reports certificate of analysis batch & lot numbers third-party testing Pinned Wiki Structured reports on named suppliers. Batch, date, method and document, or it stays in the unverified column. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit…		4	65k	18mo
About the Wiki requests category Documentation › Wiki requests wiki post promoted to docs maintainership Pinned Wiki Request a new maintained page, or flag one that has drifted out of date. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and a note.…	+3	7	655	19mo
About the Payments category Sourcing › Payments payments research use only documentation quality Pinned Wiki Payment mechanics, chargeback reality, and the recurring risks. No payment facilitation of any kind here. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…		4	3.5k	20mo
Athletes in weight-category sports: a different risk calculus — a second dataset Clinical › Special populations pregnancy & planning disordered eating bariatric surgery history Pinned On the subject in the title: Athletes in weight-category sports: a different risk calculus — a second dataset Working notes rather than a conclusion. General question, not a request for advice about my own…	+37	41	16k	20mo
Glucagon receptor agonism in a weight-loss compound Pharmacology › Receptor biology semaglutide retatrutide tirzepatide Pinned On the subject in the title: Glucagon receptor agonism in a weight-loss compound Working notes rather than a conclusion. Posting the method first, because I know what the first three replies will otherwise…		2	5.1k	20mo
Food noise reducing and the disorientation that can follow Wellbeing › Mental health beginner friendly mood disordered eating Pinned Posting this under the heading it deserves: Food noise reducing and the disorientation that can follow Everything below is what sits behind that. General question, not a request for advice about my own care —…	+40	45	8.9k	20mo
Second pass at: When a network meta-analysis is defensible and when it is not Evidence › Meta-analyses heterogeneity meta-analysis effect size publication bias Solved Pinned Posting this under the heading it deserves: Second pass at: When a network meta-analysis is defensible and when it is not Everything below is what sits behind that. Comparing STEP 8 ( JAMA , 2022) with LEADER…		2	2.8k	21mo
About the Off topic category Lounge › Off topic long read beginner friendly Pinned Wiki Anything adjacent and interesting. Not a rules-free zone, just a relaxed one. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and a…	+1	5	20k	21mo
When a red flag was a misunderstanding, and the retraction Sourcing › Red flags underdosing disputed mislabelling Pinned When a red flag was a misunderstanding, and the retraction — that is the question, and I have not found it answered plainly anywhere I have looked. I would like to talk about documentation quality as a…	+34	38	8.3k	21mo
About the International category Access › International personal import EMA MHRA Pinned Wiki Country-by-country availability and legality, dated because it changes constantly. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…	+6	11	240	22mo
About the Protein & intake category Nutrition & Training › Protein & intake lean mass loss micronutrients constipation Pinned Wiki Meeting protein targets on a suppressed appetite, fibre, and eating enough of anything at all. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with…	+4	8	9.7k	22mo
About the Introductions category Lounge › Introductions onboarding beginner friendly Pinned Wiki Closed Say hello. No question required. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and a note. If the scope described here has drifted…		4	2.3k	23mo
About the Retatrutide category Compounds › Retatrutide retatrutide TRIUMPH programme randomised trial Pinned Wiki Triple GIP/GLP-1/glucagon receptor agonist. Phase 2 data, TRIUMPH programme, and cautious practical discussion. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit…		4	12k	2y
I joined for one answer and stayed for a year — what changed my mind Start Here › Welcome guidelines onboarding trust levels Posting this under the heading it deserves: I joined for one answer and stayed for a year — what changed my mind Everything below is what sits behind that. Question in the title. Context below, and I have…	+96	114	17k	just now
What TRIUMPH is designed to answer, and why we should not pre-empt it — does this still hold? Compounds › Retatrutide randomised trial effect size TRIUMPH programme retatrutide Solved Asking directly, because I could not find a straight answer: What TRIUMPH is designed to answer, and why we should not pre-empt it — does this still hold? Session topic: STEP 2 ( Lancet , 2021). Please read…	+43	47	5.5k	just now
Rotating between abdomen, thigh and upper arm: absorption differences — one year on Practice › Administration injection site reaction needle gauge & length aseptic technique injection site rotation Rotating between abdomen, thigh and upper arm: absorption differences — one year on — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still…	+82	102	24k	just now
Journal club: indirect comparison between two programmes, defended and attacked Evidence › Journal club journal club randomised trial number needed to treat risk of bias Journal club: indirect comparison between two programmes, defended and attacked Writing it up because I had to work it out twice and would rather nobody else did. Comparing SUSTAIN 6 ( N Engl J Med , 2016)…	+122	131	5.2k	just now
eGFR fluctuation and the creatinine denominator problem — the long version Clinical › Bloodwork thyroid function eGFR & renal function liver enzymes lipase & amylase Under review eGFR fluctuation and the creatinine denominator problem — the long version — setting out what I have, and where I think it stops being reliable. Asking about a population rather than about a person. The…	+43	47	17k	just now
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Pharmacology › Receptor biology tirzepatide retatrutide amylin analogues long read Under review Receptor desensitisation as a tolerance hypothesis, and its weak evidence — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a…	+52	57	25k	just now
Reading a syringe in poor light, and how to avoid needing to Devices › Syringes & needles syringe units dead volume needle gauge & length worked example Solved Reading a syringe in poor light, and how to avoid needing to Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen…		2	22k	just now
Semaglutide formulation: what is in the licensed product besides the peptide Compounds › Semaglutide SELECT trial type 2 diabetes semaglutide Semaglutide formulation: what is in the licensed product besides the peptide — setting out what I have, and where I think it stops being reliable. Comparing LEADER ( N Engl J Med , 2016) with SURMOUNT-1 ( N…	+29	35	4.4k	1h
What consumer-accessible tests can and cannot determine Analytics › Home & field testing documentation quality ELISA third-party testing What consumer-accessible tests can and cannot determine — that is the question, and I have not found it answered plainly anywhere I have looked. Posting the method first, because I know what the first three…		2	17k	1h
Language barriers in accessing a prescription abroad Access › International personal import telehealth EMA Solved Language barriers in accessing a prescription abroad Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because everything in this…		2	22k	1h
Cleaning a self-reported dataset and what you throw away — what changed since Data & Tools › Datasets observational data site feedback data table confounding Solved Posting this under the heading it deserves: Cleaning a self-reported dataset and what you throw away — what changed since Everything below is what sits behind that. Posting the method first, because I know…		2	2k	1h
Where to report an adverse event officially, by region Safety › Adverse events pancreatitis gallbladder vomiting hypoglycaemia Solved Where to report an adverse event officially, by region Writing it up because I had to work it out twice and would rather nobody else did. Asking about a population rather than about a person. The published…		2	27k	1h
Revisiting: The best-written scientific paper you have read Lounge › Off topic beginner friendly long read Posting this under the heading it deserves: Revisiting: The best-written scientific paper you have read Everything below is what sits behind that. Lower-stakes topic, but the sourcing rule still applies if…	+102	121	21k	1h
GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Compounds › Secretagogues & GH axis CJC-1295 observational data ipamorelin needs a source Solved On the subject in the title: GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Working notes rather than a conclusion. I have seen STEP 2 ( Lancet , 2021) cited in support of…	+47	53	6.9k	2h
A widely repeated interaction claim that turns out to be unsupported — what changed since Practice › Interactions insulin hypoglycaemia metformin needs a source Solved A widely repeated interaction claim that turns out to be unsupported — what changed since Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on…	+89	94	5.9k	2h
Reference intervals: how they are constructed and why one in twenty flags — does this still hold? Clinical › Bloodwork thyroid function liver enzymes lipid panel HbA1c Solved Asking directly, because I could not find a straight answer: Reference intervals: how they are constructed and why one in twenty flags — does this still hold? General question, not a request for advice about…	+18	22	281	2h
Request: a per-category review queue Meta › Feature requests site feedback translation wiki post Request: a per-category review queue Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation commons. The topic in question…	+125	136	13k	2h