Latest topics page 5
Topics ordered by most recent activity across all 71 subcategories.
1,535 topics · page 5 of 52
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Leak-back after withdrawal and whether you lost a meaningful dose
Posting this under the heading it deserves: Leak-back after withdrawal and whether you lost a meaningful dose Everything below is what sits behind that. Reporting something rather than asking about it, in…
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2 | 3k | 3h | |
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Coming back to: Batch date after test date, and other internal inconsistencies
On the subject in the title: Batch date after test date, and other internal inconsistencies Working notes rather than a conclusion. I would like to understand what this number means before I repeat it…
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+21 | 27 | 420 | 3h |
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Revisiting: Liver enzymes drifting down and what that usually means
On the subject in the title: Revisiting: Liver enzymes drifting down and what that usually means Working notes rather than a conclusion. General question, not a request for advice about my own care — I know…
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+55 | 61 | 39k | 3h |
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What to bring: records that a clinician can actually use — a second dataset
What to bring: records that a clinician can actually use — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about a population rather than…
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+80 | 86 | 5.6k | 3h |
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Prescription portability between countries
Prescription portability between countries — setting out what I have, and where I think it stops being reliable. A coverage question with the paperwork detail included, since that is what determines the…
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+104 | 114 | 6.1k | 3h |
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Injection timing and sleep disruption
Posting this under the heading it deserves: Injection timing and sleep disruption Everything below is what sits behind that. General question, not a request for advice about my own care — I know the…
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3 | 39k | 3h | |
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Request: tag synonyms surfaced in search
On the subject in the title: Request: tag synonyms surfaced in search Working notes rather than a conclusion. Process question about how this site works. I have read the guidelines and the trust-level page…
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+23 | 27 | 38k | 3h |
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Reading order for a first week here, and what to skip until later — what changed since
Reading order for a first week here, and what to skip until later — what changed since Writing it up because I had to work it out twice and would rather nobody else did. I want to check my reasoning rather…
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+89 | 93 | 28k | 4h |
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How to ask a question when you cannot say why you are asking it
Asking directly, because I could not find a straight answer: How to ask a question when you cannot say why you are asking it Question in the title. Context below, and I have tried to include the things people…
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+49 | 53 | 36k | 4h |
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How to ask about something you suspect is a bad idea — a second dataset
How to ask about something you suspect is a bad idea — a second dataset — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title. Context below, and I…
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2 | 3.3k | 4h | |
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Reading a rodent study on a secretagogue without over-extrapolating — the long version
Reading a rodent study on a secretagogue without over-extrapolating — the long version — setting out what I have, and where I think it stops being reliable. I have seen STEP 4 ( JAMA , 2021) cited in support…
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+59 | 66 | 30k | 4h |
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What a reversed-phase purity number actually is
The question in the title: What a reversed-phase purity number actually is I will give what I have already checked below so nobody repeats it. I would like to understand what this number means before I repeat…
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+87 | 101 | 27k | 4h |
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Reused chromatograms across lots: how to spot it
On the subject in the title: Reused chromatograms across lots: how to spot it Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in front of…
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+53 | 60 | 9.5k | 4h |
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When a network meta-analysis is defensible and when it is not
When a network meta-analysis is defensible and when it is not I have a specific reason for asking rather than idle curiosity, and the context is below. Comparing SUSTAIN 6 ( N Engl J Med , 2016) with LEADER (…
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2 | 27k | 4h | |
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How the vendor documentation pages are maintained, and by whom
How the vendor documentation pages are maintained, and by whom I have a specific reason for asking rather than idle curiosity, and the context is below. I would like to talk about documentation quality as a…
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2 | 6k | 4h | |
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Mobile reading experience on long topics
Mobile reading experience on long topics Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation commons. The topic in…
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2 | 14k | 4h | |
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Named, unnamed and unspecified impurities as regulatory categories — the long version
Named, unnamed and unspecified impurities as regulatory categories — the long version — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical…
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+112 | 120 | 7.6k | 5h |
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Repeatability versus intermediate precision — what changed since
Posting this under the heading it deserves: Repeatability versus intermediate precision — what changed since Everything below is what sits behind that. Working through the identity arithmetic and I would like…
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4 | 21k | 5h | |
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Chain of custody for a sample you posted yourself
Chain of custody for a sample you posted yourself Writing it up because I had to work it out twice and would rather nobody else did. A logistics question, since the answers here are usually better than…
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2 | 7.3k | 5h | |
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Sleep quality changes during weight loss
On the subject in the title: Sleep quality changes during weight loss Working notes rather than a conclusion. Asking about a population rather than about a person. The published trials in this class mostly…
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+27 | 31 | 555 | 5h |
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What other technical communities get right that we do not
What other technical communities get right that we do not — that is the question, and I have not found it answered plainly anywhere I have looked. Lower-stakes topic, but the sourcing rule still applies if…
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+2 | 6 | 23k | 5h |
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What TRIUMPH is designed to answer, and why we should not pre-empt it
What TRIUMPH is designed to answer, and why we should not pre-empt it I have a specific reason for asking rather than idle curiosity, and the context is below. I have seen SURPASS-4 ( Lancet , 2021) cited in…
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+4 | 8 | 142 | 6h |
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Second pass at: Orforglipron as a non-peptide: what changes when the molecule is small
Second pass at: Orforglipron as a non-peptide: what changes when the molecule is small Writing it up because I had to work it out twice and would rather nobody else did. Comparing SURPASS-4 ( Lancet , 2021)…
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2 | 17k | 6h | |
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Sulfonylureas: the interaction most worth taking seriously
Sulfonylureas: the interaction most worth taking seriously Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…
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+4 | 8 | 38k | 6h |
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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree
Detection wavelength and why 214 nm and 280 nm disagree — setting out what I have, and where I think it stops being reliable. Posting the method first, because I know what the first three replies will…
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+69 | 76 | 920 | 6h |
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A supplier who responds to a discrepancy with silence — what changed since
A supplier who responds to a discrepancy with silence — what changed since — setting out what I have, and where I think it stops being reliable. A logistics question, since the answers here are usually better…
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+83 | 88 | 21k | 6h |
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Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes
Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this…
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2 | 18k | 6h | |
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[2026 update] Correlation in a self-tracked dataset: what it can support
Posting this under the heading it deserves: Correlation in a self-tracked dataset: what it can support Everything below is what sits behind that. I have seen SURMOUNT-4 ( JAMA , 2024) cited in support of a…
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2 | 31k | 6h | |
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SURPASS-2 and the comparator dose question that will not go away — what changed since
Posting this under the heading it deserves: SURPASS-2 and the comparator dose question that will not go away — what changed since Everything below is what sits behind that. Session topic: STEP 8 ( JAMA ,…
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+2 | 6 | 5.5k | 7h |
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Compounds this community declines to help with, and why — does this still hold?
Compounds this community declines to help with, and why — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. I have seen SCALE ( N Engl J Med ,…
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+3 | 7 | 26k | 7h |