Ranked by engagement

Top topics — all time page 30

Ranked by replies, likes and views over all time, with a bonus for topics that reached a marked solution. Engagement is a proxy for usefulness and a poor one; the documentation commons is the better index of what is settled.

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1,535 topics · page 30 of 40

Topic	Participants	Replies	Views	Activity
A plateau that disappeared when I changed how I measured Outcomes › Progress reports DXA long read effect size Posting this under the heading it deserves: A plateau that disappeared when I changed how I measured Everything below is what sits behind that. Longitudinal report with the method stated, because a number…	+27	31	7.2k	3mo
Whether protein timing matters at a large deficit Nutrition & Training › Protein & intake micronutrients lean mass loss fatigue Posting this under the heading it deserves: Whether protein timing matters at a large deficit Everything below is what sits behind that. Longitudinal report with the method stated, because a number without a…	+29	33	7.7k	4mo
Why one laboratory's 98.4% and another's 96.1% may not contradict Analytics › Method validation stability-indicating method LOD & LOQ linearity Solved Wiki Why one laboratory's 98.4% and another's 96.1% may not contradict I have a specific reason for asking rather than idle curiosity, and the context is below. A documentation question rather than an analytical…	+28	37	457	7mo
Sulfonylureas: the interaction most worth taking seriously Practice › Interactions needs a source metformin insulin Sulfonylureas: the interaction most worth taking seriously Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…	+4	8	38k	6h
Forced degradation studies: designing one that is informative — does this still hold? Analytics › Method validation stability-indicating method precision & repeatability LOD & LOQ system suitability Solved The question in the title: Forced degradation studies: designing one that is informative — does this still hold? I will give what I have already checked below so nobody repeats it. A documentation question…	+37	41	1.2k	12mo
About the North America category Regional › North America FDA compounding insurance Pinned Wiki US and Canadian regulation, compounding, and coverage. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author and a note. If the scope…	+3	7	43k	9mo
Severe abdominal pain: why this is not a forum question — one year on Safety › Adverse events pancreatitis delayed gastric emptying gallbladder vomiting Closed Severe abdominal pain: why this is not a forum question — one year on — setting out what I have, and where I think it stops being reliable. General question, not a request for advice about my own care — I…		2	49k	10mo
Revisiting: Oral versus injected administration claims for BPC-157 Compounds › Repair & healing peptides observational data needs a source TB-500 BPC-157 Solved On the subject in the title: Revisiting: Oral versus injected administration claims for BPC-157 Working notes rather than a conclusion. I have seen SELECT ( N Engl J Med , 2023) cited in support of a claim I…	+23	27	7.7k	15mo
Why quantitation is the hard part, not detection Analytics › Home & field testing LOD & LOQ third-party testing ELISA Why quantitation is the hard part, not detection I have a specific reason for asking rather than idle curiosity, and the context is below. Posting the method first, because I know what the first three replies…	+11	15	27k	12mo
IGF-1 as a surrogate endpoint and its limitations Compounds › Secretagogues & GH axis GHRP class needs a source observational data tesamorelin IGF-1 as a surrogate endpoint and its limitations Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURPASS-4 ( Lancet , 2021) cited in support of a claim I do not…	+5	9	35k	4mo
Two scans six weeks apart on different machines: a cautionary tale Outcomes › Body composition lean mass loss data table bioimpedance DXA Solved On the subject in the title: Two scans six weeks apart on different machines: a cautionary tale Working notes rather than a conclusion. Longitudinal report with the method stated, because a number without a…	+18	26	9.4k	2mo
Cost per milligram, computed honestly across formats Access › Pricing formulary cost per milligram data table Posting this under the heading it deserves: Cost per milligram, computed honestly across formats Everything below is what sits behind that. Documenting an access outcome, dated, because everything in this…		2	47k	18mo
A revision dispute resolved on the topic rather than in the history Meta › Wiki maintenance wiki post maintainership moderation citation check A revision dispute resolved on the topic rather than in the history Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation…	+11	15	40k	16h
Dizziness on standing: the ordinary explanation first Nutrition & Training › Hydration & electrolytes blood pressure heart rate fatigue Posting this under the heading it deserves: Dizziness on standing: the ordinary explanation first Everything below is what sits behind that. Longitudinal report with the method stated, because a number…	+22	26	27k	15mo
Follow-up: Evidence quality in the secretagogue literature: an honest assessment Compounds › Secretagogues & GH axis CJC-1295 ipamorelin tesamorelin needs a source On the subject in the title: Evidence quality in the secretagogue literature: an honest assessment Working notes rather than a conclusion. Comparing PIONEER 6 ( N Engl J Med , 2019) with LEADER ( N Engl J Med…	+20	24	18k	4mo
Hair shedding at month three: mechanism and time course Practice › Side effects delayed gastric emptying fatigue constipation hair shedding On the subject in the title: Hair shedding at month three: mechanism and time course Working notes rather than a conclusion. Reporting something rather than asking about it, in case the pattern is useful to…		2	47k	7mo
About the Syringes & needles category Devices › Syringes & needles syringe units dead volume needle gauge & length Pinned Wiki Insulin syringe graduations, dead volume, gauge and length selection, and reading units correctly. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…		4	45k	1mo
"Should I double up?" — answered once, at length, calmly Practice › Administration subcutaneous injection missed dose injection site reaction "Should I double up?" — answered once, at length, calmly — setting out what I have, and where I think it stops being reliable. Practical question with the units stated, because I have seen how quickly these…	+24	28	13k	9mo
What the GIP component of tirzepatide is thought to contribute, and how confident we can be Compounds › Tirzepatide tirzepatide SURPASS programme SURMOUNT programme effect size Solved What the GIP component of tirzepatide is thought to contribute, and how confident we can be I have a specific reason for asking rather than idle curiosity, and the context is below. Comparing STEP 1 ( N Engl…	+16	20	23k	19h
Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Clinical › Comorbidities chronic kidney disease blood pressure obstructive sleep apnoea On the subject in the title: Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Working notes rather than a conclusion. General question, not a request for advice about my own care…	+4	8	43k	17mo
What a seizure notice actually says Sourcing › Logistics shipping packaging customs Solved What a seizure notice actually says I have a specific reason for asking rather than idle curiosity, and the context is below. A logistics question, since the answers here are usually better than anywhere else…	+36	40	568	17mo
What a certificate commits its issuer to — the long version Analytics › COA interpretation batch & lot numbers amino acid analysis reference standards certificate of analysis Asking directly, because I could not find a straight answer: What a certificate commits its issuer to — the long version A documentation question rather than an analytical one. I have a certificate in front…	+20	26	21k	2d
Gradient steepness and apparent purity: a worked comparison Analytics › HPLC & UHPLC data table UV & DAD detection peak integration HPLC On the subject in the title: Gradient steepness and apparent purity: a worked comparison Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in…		2	51k	22mo
Request declined, with reasoning — what changed since Meta › Feature requests wiki post site feedback translation Posting this under the heading it deserves: Request declined, with reasoning — what changed since Everything below is what sits behind that. Process question about how this site works. I have read the…	+34	38	9.4k	2mo
Shoulders, tangent skims, and defensible integration — the long version Analytics › HPLC & UHPLC HPLC system suitability peak integration data table Shoulders, tangent skims, and defensible integration — the long version Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first, because I know what the…	+16	20	27k	3mo
Cagrilintide molecular characteristics and analytical considerations Compounds › Cagrilintide & amylin analogues cagrilintide randomised trial amylin analogues cagrisema Cagrilintide molecular characteristics and analytical considerations — setting out what I have, and where I think it stops being reliable. I have seen SURMOUNT-2 ( Lancet , 2023) cited in support of a claim I…		4	41k	12mo
Why cagrilintide alone is discussed so much less than in combination — does this still hold? Compounds › Cagrilintide & amylin analogues cagrisema randomised trial cagrilintide effect size Solved Under review Why cagrilintide alone is discussed so much less than in combination — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Session topic: SURMOUNT-4…	+27	31	1.2k	22h
MHRA statements, read directly — the long version Regional › UK & Ireland MHRA cost per milligram personal import NHS On the subject in the title: MHRA statements, read directly — the long version Working notes rather than a conclusion. Documenting an access outcome, dated, because everything in this category expires. As of…		2	44k	22mo
Water content on a certificate and why it changes the arithmetic Analytics › COA interpretation certificate of analysis reference standards batch & lot numbers Closed Water content on a certificate and why it changes the arithmetic — setting out what I have, and where I think it stops being reliable. A documentation question rather than an analytical one. I have a…	+19	23	24k	14mo
Recording a dissent on a document rather than suppressing it Documentation › Doc review maintainership promoted to docs citation check Solved Recording a dissent on a document rather than suppressing it Writing it up because I had to work it out twice and would rather nobody else did. Process question about how this site works. I have read the…	+15	19	25k	1mo