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Topics ordered by when they were created rather than by activity. This is where a question that nobody has answered yet is easiest to find — and answering one is the fastest route to a first solution badge.

1,535 topics · page 11 of 40

Topic	Participants	Replies	Views	Activity
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Practice › Reconstitution syringe units worked example reconstitution bacteriostatic water Solved A 5 mg vial and a 0.25 mg dose: the arithmetic in full Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…	+124	141	16k	2d
Labelling requirements for research chemicals Sourcing › Regulatory research use only MHRA FDA Under review Labelling requirements for research chemicals — setting out what I have, and where I think it stops being reliable. Structured report rather than an opinion, following the format the maintainers asked for.…	+5	9	45k	4mo
Sample handling between despatch and injection Analytics › Method validation stability-indicating method LOD & LOQ linearity precision & repeatability Sample handling between despatch and injection Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first, because I know what the first three replies will…	+63	68	2.4k	3mo
What to include when your question involves a laboratory result Start Here › How to Ask beginner friendly site feedback guidelines Asking directly, because I could not find a straight answer: What to include when your question involves a laboratory result Question in the title. Context below, and I have tried to include the things people…	+8	12	14k	2d
Vomiting: when it is expected and when it is a reason to stop — one year on Practice › Side effects nausea vomiting hair shedding Vomiting: when it is expected and when it is a reason to stop — one year on Writing it up because I had to work it out twice and would rather nobody else did. Reporting something rather than asking about it,…	+19	23	49k	18h
Does a peptide degrade silently, with no visual change? Practice › Storage & stability beyond-use date cold chain temperature excursion freeze-thaw Solved Does a peptide degrade silently, with no visual change? I have a specific reason for asking rather than idle curiosity, and the context is below. I have read the maintained page on this and I still have a…	+73	79	1.3k	1d
Revisiting: Mobile reading experience on long topics Meta › Site feedback moderation guidelines site feedback Solved Posting this under the heading it deserves: Revisiting: Mobile reading experience on long topics Everything below is what sits behind that. Nominating something for promotion into the documentation commons.…	+11	15	34k	10h
When a network meta-analysis is defensible and when it is not Evidence › Meta-analyses effect size heterogeneity publication bias Solved When a network meta-analysis is defensible and when it is not I have a specific reason for asking rather than idle curiosity, and the context is below. Comparing SUSTAIN 6 ( N Engl J Med , 2016) with LEADER (…		2	27k	4h
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Devices › Syringes & needles syringe units subcutaneous injection needle gauge & length dead volume Wiki 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters — setting out what I have, and where I think it stops being reliable. Practical question with the units stated, because I have seen how quickly…	+104	114	6k	6d
Shakes versus food: a pragmatic assessment Nutrition & Training › Protein & intake lean mass loss micronutrients constipation Shakes versus food: a pragmatic assessment Writing it up because I had to work it out twice and would rather nobody else did. Maintenance rather than loss, which is the part of this that almost nobody writes…	+22	26	53k	20h
Area percent versus weight percent: the confusion that causes most arguments Analytics › HPLC & UHPLC system suitability UV & DAD detection HPLC data table Posting this under the heading it deserves: Area percent versus weight percent: the confusion that causes most arguments Everything below is what sits behind that. Posting the method first, because I know…	+10	14	2.1k	2mo
Light exposure: how much protection is proportionate? Practice › Storage & stability beyond-use date freeze-thaw cold chain cloudy or discoloured solution The question in the title: Light exposure: how much protection is proportionate? I will give what I have already checked below so nobody repeats it. A question about technique rather than about dose. I have…		2	59	3mo
Reflectance and photometric devices: precision in practice — a second dataset Analytics › Home & field testing ELISA LOD & LOQ documentation quality Reflectance and photometric devices: precision in practice — a second dataset — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I…	+75	82	17k	12h
Chain of custody for a sample you posted yourself Sourcing › Independent verification PeptideMeter third-party testing Janoshik Analytical blind sampling Chain of custody for a sample you posted yourself Writing it up because I had to work it out twice and would rather nobody else did. A logistics question, since the answers here are usually better than…		2	7.3k	5h
Second pass at: Why chargeback is not the safety net people assume Sourcing › Payments documentation quality research use only payments Solved Second pass at: Why chargeback is not the safety net people assume Writing it up because I had to work it out twice and would rather nobody else did. A logistics question, since the answers here are usually…		2	25k	3mo
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Analytics › Method validation precision & repeatability LOD & LOQ linearity Specificity, linearity, accuracy, precision, range, robustness — with real criteria Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this…	+44	48	12k	1d
Washout with a one-week half-life: the arithmetic — does this still hold? Research Methods › N-of-1 designs confounding data table worked example Solved Washout with a one-week half-life: the arithmetic — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing SURPASS-2 ( N Engl J Med , 2021)…	+41	45	12k	1d
Revisiting: Can a home kit substitute for a laboratory report? A careful no Analytics › Home & field testing ELISA LOD & LOQ documentation quality third-party testing Revisiting: Can a home kit substitute for a laboratory report? A careful no — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like it…	+50	56	9.8k	1d
Journal club: is percentage weight change the right endpoint? Evidence › Journal club number needed to treat randomised trial journal club Solved Journal club: is percentage weight change the right endpoint? I have a specific reason for asking rather than idle curiosity, and the context is below. Comparing SURPASS-4 ( Lancet , 2021) with SURMOUNT-OSA (…	+116	120	23k	3mo
The anatomy of a question that gets answered within an hour Start Here › How to Ask worked example site feedback onboarding beginner friendly Wiki The anatomy of a question that gets answered within an hour — setting out what I have, and where I think it stops being reliable. Question in the title. Context below, and I have tried to include the things…	+113	127	2.7k	13h
Second pass at: Sleep apnoea improving and the equipment implications Wellbeing › Sleep fatigue heart rate obstructive sleep apnoea On the subject in the title: Second pass at: Sleep apnoea improving and the equipment implications Working notes rather than a conclusion. General question, not a request for advice about my own care — I know…	+89	96	1.1k	10h
Fasting versus non-fasting and which tests care Clinical › Bloodwork eGFR & renal function lipase & amylase HbA1c Solved Fasting versus non-fasting and which tests care Writing it up because I had to work it out twice and would rather nobody else did. General question, not a request for advice about my own care — I know the…	+72	78	14k	19h
Journal club: the CagriSema phase 2 combination paper Evidence › Journal club randomised trial estimand effect size On the subject in the title: Journal club: the CagriSema phase 2 combination paper Working notes rather than a conclusion. I have seen SURMOUNT-1 ( N Engl J Med , 2022) cited in support of a claim I do not…		2	329	21h
Coming back to: Which fields on a certificate actually matter, ranked Analytics › COA interpretation reference standards documentation quality batch & lot numbers amino acid analysis Solved Which fields on a certificate actually matter, ranked I have a specific reason for asking rather than idle curiosity, and the context is below. Posting the method first, because I know what the first three…		2	15k	4mo
Follow-up: Levothyroxine timing: a real interaction with a simple fix Practice › Interactions metformin needs a source hypoglycaemia insulin Closed On the subject in the title: Levothyroxine timing: a real interaction with a simple fix Working notes rather than a conclusion. Reporting something rather than asking about it, in case the pattern is useful…	+2	6	8.1k	4mo
Type 2 diabetes and the largest part of the evidence base — does this still hold? Clinical › Comorbidities type 2 diabetes chronic kidney disease PCOS blood pressure Solved Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about a population rather…	+17	22	4.5k	1d
What a documentation review can and cannot tell you — a second dataset Sourcing › Independent verification Janoshik Analytical VendorInvestigate blind sampling third-party testing The question in the title: What a documentation review can and cannot tell you — a second dataset I will give what I have already checked below so nobody repeats it. I would like to talk about documentation…		4	170	4mo
Secretagogues and glucose tolerance: the mechanistic concern — what changed since Compounds › Secretagogues & GH axis GHRP class ipamorelin CJC-1295 observational data Wiki Closed Secretagogues and glucose tolerance: the mechanistic concern — what changed since Writing it up because I had to work it out twice and would rather nobody else did. I have seen STEP 1 ( N Engl J Med , 2021)…	+2	6	31k	2mo
Spreadsheets: an appreciation — what changed since Lounge › Off topic long read beginner friendly Spreadsheets: an appreciation — what changed since — setting out what I have, and where I think it stops being reliable. Lower-stakes topic, but the sourcing rule still applies if anyone makes a claim.…	+102	113	26k	17h
Why the absence of controlled human data on BPC-157 matters more than people admit Compounds › Repair & healing peptides needs a source BPC-157 preprint Solved Why the absence of controlled human data on BPC-157 matters more than people admit — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing STEP 8 ( JAMA , 2022) with…	+60	66	16k	1d