Latest topics page 40

Topics ordered by most recent activity across all 71 subcategories.

1,535 topics · page 40 of 52

Topic	Participants	Replies	Views	Activity
Insulin combinations and hypoglycaemia risk Practice › Interactions metformin needs a source hypoglycaemia insulin Closed On the subject in the title: Insulin combinations and hypoglycaemia risk Working notes rather than a conclusion. Practical question with the units stated, because I have seen how quickly these go wrong…	+18	22	7.8k	13mo
Area percent versus weight percent: the confusion that causes most arguments — what changed since Analytics › HPLC & UHPLC gradient method data table HPLC Area percent versus weight percent: the confusion that causes most arguments — what changed since Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first,…	+30	34	40k	13mo
Splitting a vial for two laboratories: how to do it without ruining both Sourcing › Independent verification blind sampling PeptideMeter third-party testing Medutest Solved Splitting a vial for two laboratories: how to do it without ruining both — setting out what I have, and where I think it stops being reliable. A logistics question, since the answers here are usually better…	+64	70	4.4k	13mo
Coming back to: Request: tag synonyms surfaced in search Meta › Feature requests site feedback wiki post translation Solved Request: tag synonyms surfaced in search Writing it up because I had to work it out twice and would rather nobody else did. Process question about how this site works. I have read the guidelines and the…		2	26k	13mo
[2026 update] Dose numbers across compounds are not on the same scale Practice › Dosing & titration dose reduction worked example semaglutide titration On the subject in the title: Dose numbers across compounds are not on the same scale Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking…	+14	18	1.2k	13mo
The report format the maintainers ask for, and why each field is there — what changed since Sourcing › Vendor reports third-party testing disputed Janoshik Analytical The report format the maintainers ask for, and why each field is there — what changed since Writing it up because I had to work it out twice and would rather nobody else did. Structured report rather than an…	+29	35	6.6k	13mo
Reading an MS report that only gives you a single number Analytics › Mass spectrometry counter-ion content mass error (ppm) charge states On the subject in the title: Reading an MS report that only gives you a single number Working notes rather than a conclusion. I would like to understand what this number means before I repeat it anywhere. A…	+100	113	48k	13mo
The CagriSema phase 2 paper and what a fixed combination buys — the long version Compounds › Cagrilintide & amylin analogues amylin analogues cagrisema cagrilintide The CagriSema phase 2 paper and what a fixed combination buys — the long version Writing it up because I had to work it out twice and would rather nobody else did. I have seen STEP 1 ( N Engl J Med , 2021)…	+137	158	17k	13mo
Follow-up: Requesting a page: what makes a good request Documentation › Wiki requests promoted to docs review date maintainership wiki post Solved On the subject in the title: Requesting a page: what makes a good request Working notes rather than a conclusion. Nominating something for promotion into the documentation commons. The topic in question keeps…	+44	50	64k	13mo
[2026 update] Gastro-oesophageal reflux: improving or worsening? Clinical › Comorbidities chronic kidney disease MASH / hepatic steatosis PCOS blood pressure Solved Asking directly, because I could not find a straight answer: Gastro-oesophageal reflux: improving or worsening? General question, not a request for advice about my own care — I know the difference and I would…		3	782	13mo
Second pass at: Retatrutide mass and identity: what a report should show Compounds › Retatrutide retatrutide randomised trial effect size Solved Second pass at: Retatrutide mass and identity: what a report should show — setting out what I have, and where I think it stops being reliable. Comparing SURMOUNT-2 ( Lancet , 2023) with STEP 4 ( JAMA , 2021)…	+65	71	4.6k	13mo
Cost per milligram, computed honestly across formats — a second dataset Access › Pricing cost per milligram formulary compounding Closed Cost per milligram, computed honestly across formats — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. A coverage question with the paperwork detail…		2	27k	13mo
A 5 mg vial and a 0.25 mg dose: the arithmetic in full — what changed since Practice › Reconstitution dead volume bacteriostatic water reconstitution syringe units Closed Posting this under the heading it deserves: A 5 mg vial and a 0.25 mg dose: the arithmetic in full — what changed since Everything below is what sits behind that. I have read the maintained page on this and I…	+86	93	25k	13mo
Second pass at: Pen dose counters: what a click does and does not guarantee Devices › Pens & autoinjectors dead volume storage subcutaneous injection Second pass at: Pen dose counters: what a click does and does not guarantee — setting out what I have, and where I think it stops being reliable. A question about technique rather than about dose. I have been…	+63	68	51k	13mo
[2026 update] An appeal that failed, and what I would do differently Access › Insurance & coverage prior authorisation insurance formulary Posting this under the heading it deserves: An appeal that failed, and what I would do differently Everything below is what sits behind that. Documenting an access outcome, dated, because everything in this…	+152	159	2.5k	13mo
Half-life, steady state, and accumulation worked through Pharmacology › Pharmacokinetics semaglutide liraglutide tirzepatide Wiki Half-life, steady state, and accumulation worked through Writing it up because I had to work it out twice and would rather nobody else did. Working through the identity arithmetic and I would like it checked.…	+115	130	44k	13mo
Lipase elevation without symptoms: the interpretation problem — a second dataset Clinical › Bloodwork lipid panel liver enzymes HbA1c eGFR & renal function Wiki Closed Posting this under the heading it deserves: Lipase elevation without symptoms: the interpretation problem — a second dataset Everything below is what sits behind that. General question, not a request for…	+6	15	2.2k	13mo
Follow-up: Tracking intake honestly when appetite is absent Nutrition & Training › Protein & intake constipation micronutrients lean mass loss fatigue Solved Tracking intake honestly when appetite is absent Writing it up because I had to work it out twice and would rather nobody else did. Longitudinal report with the method stated, because a number without a…	+94	106	1.8k	13mo
Coming back to: Getting a referral rather than a refusal Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes beginner friendly Solved Posting this under the heading it deserves: Getting a referral rather than a refusal Everything below is what sits behind that. General question, not a request for advice about my own care — I know the…	+69	74	1.7k	13mo
Validating a calculator against hand arithmetic — what changed since Data & Tools › Calculators concentration maths site feedback worked example Solved Posting this under the heading it deserves: Validating a calculator against hand arithmetic — what changed since Everything below is what sits behind that. Working through the identity arithmetic and I would…	+121	137	21k	13mo
Second pass at: Trial registration and comparing the protocol with the paper Evidence › Trials estimand discontinuation & dropout randomised trial open label Posting this under the heading it deserves: Second pass at: Trial registration and comparing the protocol with the paper Everything below is what sits behind that. I have seen SCALE ( N Engl J Med , 2015)…	+30	34	33k	13mo
Merging two pages that cover the same ground Documentation › Wiki requests wiki post promoted to docs maintainership Merging two pages that cover the same ground Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation commons. The topic in…		2	888	13mo
Follow-up: How much fluid is actually needed, and how you would know Nutrition & Training › Hydration & electrolytes blood pressure heart rate fatigue How much fluid is actually needed, and how you would know — that is the question, and I have not found it answered plainly anywhere I have looked. Maintenance rather than loss, which is the part of this that…	+17	21	12k	13mo
Needle changes between doses on a reusable pen — does this still hold? Devices › Pens & autoinjectors dead volume missed dose storage Solved Wiki Needle changes between doses on a reusable pen — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. I have read the maintained page on this and I…	+1	5	38k	13mo
Second pass at: A payment that went through twice: how it was resolved Sourcing › Payments research use only documentation quality payments On the subject in the title: Second pass at: A payment that went through twice: how it was resolved Working notes rather than a conclusion. A logistics question, since the answers here are usually better than…		2	1.1k	14mo
Price changes over 2025 and 2026, tabulated and dated Access › Pricing formulary cost per milligram data table compounding Posting this under the heading it deserves: Price changes over 2025 and 2026, tabulated and dated Everything below is what sits behind that. Documenting an access outcome, dated, because everything in this…	+4	8	658	14mo
Follow-up: What other technical communities get right that we do not Lounge › Off topic long read beginner friendly What other technical communities get right that we do not I have a specific reason for asking rather than idle curiosity, and the context is below. Lower-stakes topic, but the sourcing rule still applies if…	+117	126	13k	14mo
Individual participant data versus aggregate data Evidence › Meta-analyses heterogeneity risk of bias meta-analysis publication bias Posting this under the heading it deserves: Individual participant data versus aggregate data Everything below is what sits behind that. Session topic: SCALE ( N Engl J Med , 2015). Please read it before…	+30	34	64k	14mo
When a preprint is the best available evidence and we say so — a second dataset Evidence › Preprints preprint risk of bias needs a source Solved When a preprint is the best available evidence and we say so — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. I have seen SUSTAIN 6 ( N Engl J Med ,…	+20	24	36k	14mo
Storing a pen in use versus a pen unopened Devices › Pens & autoinjectors storage missed dose dead volume Storing a pen in use versus a pen unopened Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how quickly these go…	+14	18	13k	14mo