Latest topics page 43

Topics ordered by most recent activity across all 71 subcategories.

1,535 topics · page 43 of 52

Topic	Participants	Replies	Views	Activity
When "no data" is the complete and final answer Compounds › Other compounds custom synthesis mislabelling needs a source research use only Solved Asking directly, because I could not find a straight answer: When "no data" is the complete and final answer I have seen SURMOUNT-1 ( N Engl J Med , 2022) cited in support of a claim I do not think it…	+154	165	6.3k	15mo
Transit times by route, from a logged dataset — the long version Sourcing › Logistics cold chain shipping customs Wiki Closed Posting this under the heading it deserves: Transit times by route, from a logged dataset — the long version Everything below is what sits behind that. I would like to talk about documentation quality as a…	+82	87	8.9k	15mo
Scheduled maintenance and what will be unavailable Meta › Announcements guidelines trust levels moderation site feedback Scheduled maintenance and what will be unavailable Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation commons. The…	+121	128	25k	15mo
Dizziness on standing: the ordinary explanation first Nutrition & Training › Hydration & electrolytes blood pressure heart rate fatigue Posting this under the heading it deserves: Dizziness on standing: the ordinary explanation first Everything below is what sits behind that. Longitudinal report with the method stated, because a number…	+22	26	27k	15mo
Journal club: STEP 4 and what a withdrawal design can prove — one year on Evidence › Journal club number needed to treat estimand randomised trial effect size Closed Journal club: STEP 4 and what a withdrawal design can prove — one year on Writing it up because I had to work it out twice and would rather nobody else did. Session topic: SURMOUNT-OSA ( N Engl J Med , 2024).…	+56	62	34k	15mo
Filing a first vendor report: a worked example Sourcing › Vendor reports third-party testing batch & lot numbers Janoshik Analytical documentation quality Filing a first vendor report: a worked example Writing it up because I had to work it out twice and would rather nobody else did. A logistics question, since the answers here are usually better than anywhere…	+1	5	12k	15mo
Review: a draft on reconstitution arithmetic, with objections Documentation › Doc review wiki post promoted to docs citation check Review: a draft on reconstitution arithmetic, with objections Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation…	+120	129	4.1k	15mo
Certificates issued by the seller versus by a laboratory Analytics › COA interpretation amino acid analysis certificate of analysis documentation quality Posting this under the heading it deserves: Certificates issued by the seller versus by a laboratory Everything below is what sits behind that. I would like to understand what this number means before I…	+58	65	1.2k	15mo
Reaching a dose and staying there for a year: a longitudinal note Practice › Dosing & titration worked example tirzepatide titration semaglutide Reaching a dose and staying there for a year: a longitudinal note Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I still have a…		2	763	15mo
Requesting a page: what makes a good request Documentation › Wiki requests wiki post maintainership promoted to docs review date Requesting a page: what makes a good request Writing it up because I had to work it out twice and would rather nobody else did. Nominating something for promotion into the documentation commons. The topic in…	+65	71	9.3k	15mo
Second pass at: Gauge and length selection for subcutaneous injection Devices › Syringes & needles subcutaneous injection syringe units worked example needle gauge & length Posting this under the heading it deserves: Second pass at: Gauge and length selection for subcutaneous injection Everything below is what sits behind that. A question about technique rather than about dose.…	+50	58	14k	15mo
Adducts: sodium, potassium, and the peak you did not expect Analytics › Mass spectrometry LC-MS MALDI-TOF mass error (ppm) Wiki Adducts: sodium, potassium, and the peak you did not expect Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means before I repeat…	+70	77	3.5k	15mo
Over-dilution: when your dose falls below one readable graduation Practice › Reconstitution concentration maths syringe units bacteriostatic water dead volume On the subject in the title: Over-dilution: when your dose falls below one readable graduation Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am…	+15	19	248	15mo
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Evidence › Journal club risk of bias number needed to treat randomised trial Asking directly, because I could not find a straight answer: Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Comparing STEP 2 ( Lancet , 2021) with SURMOUNT-4 ( JAMA , 2024) and…	+118	132	12k	15mo
Hello from a laboratory that does not do peptides Lounge › Introductions onboarding beginner friendly Hello from a laboratory that does not do peptides — setting out what I have, and where I think it stops being reliable. Lower-stakes topic, but the sourcing rule still applies if anyone makes a claim.…	+2	6	10k	15mo
Storing a pen in use versus a pen unopened — what changed since Devices › Pens & autoinjectors subcutaneous injection dead volume missed dose Posting this under the heading it deserves: Storing a pen in use versus a pen unopened — what changed since Everything below is what sits behind that. I have read the maintained page on this and I still have…		2	206	15mo
Retatrutide dose escalation in the published trials Compounds › Retatrutide preprint retatrutide effect size Posting this under the heading it deserves: Retatrutide dose escalation in the published trials Everything below is what sits behind that. Session topic: SURPASS-2 ( N Engl J Med , 2021). Please read it…	+149	159	30k	15mo
UK access routes, dated and sourced Regional › UK & Ireland NHS personal import MHRA Closed UK access routes, dated and sourced Writing it up because I had to work it out twice and would rather nobody else did. Documenting an access outcome, dated, because everything in this category expires. As of…		2	5.8k	15mo
Excipient function in a licensed injectable — the long version Pharmacology › Formulation chemistry sterile water storage bacteriostatic water Posting this under the heading it deserves: Excipient function in a licensed injectable — the long version Everything below is what sits behind that. Working through the identity arithmetic and I would like…		2	100	15mo
Review cadence: how often is a page actually re-checked? Documentation › Doc review maintainership review date promoted to docs Solved Asking directly, because I could not find a straight answer: Review cadence: how often is a page actually re-checked? Nominating something for promotion into the documentation commons. The topic in question…	+20	24	20k	15mo
When to suspect the method rather than the sample Analytics › Method validation recovery stability-indicating method linearity system suitability Solved When to suspect the method rather than the sample — that is the question, and I have not found it answered plainly anywhere I have looked. Posting the method first, because I know what the first three replies…	+109	115	63k	15mo
Electrolyte supplements: which ones do anything — a second dataset Nutrition & Training › Hydration & electrolytes fatigue heart rate blood pressure Electrolyte supplements: which ones do anything — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Maintenance rather than loss, which is the part of this…		2	59k	15mo
Sample size in a voluntary survey: the selection problem Data & Tools › Datasets observational data data table site feedback Solved Posting this under the heading it deserves: Sample size in a voluntary survey: the selection problem Everything below is what sits behind that. Posting the method first, because I know what the first three…	+1	5	12k	15mo
Carryover and the ghost peak from last week's standard Analytics › HPLC & UHPLC data table UV & DAD detection peak integration system suitability On the subject in the title: Carryover and the ghost peak from last week's standard Working notes rather than a conclusion. Posting the method first, because I know what the first three replies will otherwise…	+80	92	16k	16mo
Injection timing and sleep disruption — the long version Wellbeing › Sleep obstructive sleep apnoea heart rate fatigue Injection timing and sleep disruption — the long version — setting out what I have, and where I think it stops being reliable. Asking about a population rather than about a person. The published trials in…		2	164	16mo
A certificate with no method stated: what can you conclude? Analytics › COA interpretation certificate of analysis batch & lot numbers documentation quality Solved A certificate with no method stated: what can you conclude? I have a specific reason for asking rather than idle curiosity, and the context is below. I would like to understand what this number means before I…	+49	57	1.2k	16mo
Follow-up: Journal club: the retatrutide phase 2 obesity paper Evidence › Journal club randomised trial risk of bias effect size journal club Closed On the subject in the title: Journal club: the retatrutide phase 2 obesity paper Working notes rather than a conclusion. I have seen SURMOUNT-1 ( N Engl J Med , 2022) cited in support of a claim I do not…	+20	24	8.7k	16mo
A supplier who responds to a discrepancy with silence Sourcing › Red flags underdosing documentation quality moderation mislabelling Closed On the subject in the title: A supplier who responds to a discrepancy with silence Working notes rather than a conclusion. Structured report rather than an opinion, following the format the maintainers asked…		2	6.1k	16mo
Why appetite effects are mostly central Pharmacology › Receptor biology amylin analogues tirzepatide semaglutide long read Why appetite effects are mostly central I have a specific reason for asking rather than idle curiosity, and the context is below. Posting the method first, because I know what the first three replies will…		2	56k	16mo
Follow-up: Review cadence: how often is a page actually re-checked? Documentation › Doc review wiki post citation check maintainership promoted to docs Solved The question in the title: Review cadence: how often is a page actually re-checked? I will give what I have already checked below so nobody repeats it. Nominating something for promotion into the…		2	64k	16mo